2014年2月19日星期三

The story of Naphthalene

Naphthalene is made from crude oil or coal tar. It is also produced when things burn, so Naphthalene is found in cigarette smoke, car exhaust, and smoke from forest fires. It is used as an insecticide and pest repellent.

The primary use for Naphthalene(CAS NO:91-20-3) is in the production of phthalic anhydride. However, o-xylene is replacing Naphthalene as the preferred raw material for phthalic anhydride production.Other uses of Naphthalene include carbamate insecticides, surface active agents and resins, as a dye intermediate, as a synthetic tanning agent, as a moth repellent, and in miscellaneous organic chemicals. 

Naphthalene was first registered as a pesticide in the United States in 1948.In early 1820, two chemists, in two separate reports, described a white solid with a pungent odor derived from the distillation of coal tar. In 1821, John Kidd cited these two disclosures and then described many of this substance's properties and the means of its production. 

He proposed the name Naphthalene, as it had been derived from a kind of naphtha. Naphthalene's chemical formula was determined by Michael Faraday in 1826. The structure of two fused benzene rings was proposed by Emil Erlenmeyer in 1866, and confirmed by Carl Gräbe three years later.

Most Naphthalene is derived from coal tar. From the 1960s until the 1990s, significant amounts of Naphthalene were also produced from heavy petroleum fractions during petroleum refining, but today petroleum-derived Naphthalene represents only a minor component of Naphthalene production.

Naphthalene is the most abundant single component of coal tar. Although the composition of coal tar varies with the coal from which it is produced, typical coal tar is about 10% Naphthalene by weight. In industrial practice, distillation of coal tar yields an oil containing about 50% Naphthalene, along with a variety of other aromatic compounds. This oil, after being washed with aqueous sodium hydroxide to remove acidic components (chiefly various phenols), and with sulfuric acid to remove basic components, undergoes fractional distillation to isolate Naphthalene.

 The crude Naphthalene(CAS NO:91-20-3) resulting from this process is about 95% Naphthalene by weight. The chief impurities are the sulfur-containing aromatic compound benzothiophene, indane, indene, and methylNaphthalene . Petroleum-derived Naphthalene is usually purer than that derived from coal tar. Where required, crude Naphthalene can be further purified by recrystallization from any of a variety of solvents, resulting in 99% Naphthalene by weight, referred to as 80 C (melting point). Approximately 1.3M tons are produced annually.

In North America, coal tar producers are Koppers Inc. and Recochem Inc., and petroleum-derived producer is Advanced Aromatics, L.P. In Western Europe most known producers are Koppers, Ruetgers and Deza. In Eastern Europe, variety of integrated metallurgy complexes in Russia. Dedicated Naphthalene and phenol maker INKOR and Yenakievsky Metallurgy plant in Ukraine, and ArcelorMittal Temirtau in Kazakhstan.

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2014年2月18日星期二

How does Ezetimibe work ?

Ezetimibe localises at the brush border of the small intestine, where it inhibits the absorption of cholesterol from the intestine. Specifically, it appears to bind to a critical mediator of cholesterol absorption, the Niemann-Pick C1-Like 1 protein on the gastrointestinal tract epithelial cells as well as in hepatocytes.

Ezetimibe is used along with a low cholesterol/low fat diet and exercise to help lower cholesterol in the blood. It may be used alone or with other drugs. Ezetimibe(CAS NO:163222-33-1) works by reducing the amount of cholesterol your body absorbs from your diet. Reducing cholesterol may help prevent strokes and heart attacks.

Side effects of Ezetimibe include gastrointestinal disturbances, headache, fatigue, myalgia; rarely arthralgia, hypersensitivity reactions (including rash, angioedema, and anaphylaxis), hepatitis; AND very rarely pancreatitis, cholelithiasis, cholecystitis, thrombocytopenia, raised creatine kinase, myopathy, and rhabdomyolysis.

But how does Ezetimibe work? In this article, I will show you it on the every usages of Ezetimibe.

Ezetrol tablets contain the active ingredient ezetimibe, which is type of medicine known as a cholesterol absorption inhibitor. It is used to lower high cholesterol levels.

Ezetimibe works by preventing cholesterol from being absorbed from the small intestine into the bloodstream. It prevents cholesterol and other plant sterols that are consumed in the diet from being absorbed into the bloodstream. It also prevents cholesterol released from the bile duct into the intestine from being reabsorbed into the bloodstream. The overall result is a reduction in cholesterol levels in the blood.

Ezetimibe may also be used on its own to lower cholesterol in people with primary hypercholesterolaemia who cannot take statins. Ezetimibe is used in conjunction with a statin and a cholesterol-lowering diet to lower cholesterol in people with inherited high cholesterol levels .

Ezetimibe(CAS NO:163222-33-1) is used to lower cholesterol in people with high cholesterol levels. It is normally used when another type of cholesterol-lowering medicine called a statin, together with a low cholesterol diet and increased exercise, has not lowered cholesterol sufficiently. Ezetimibe is added to the statin treatment because it works in a different way to statins and so it can boost their cholesterol lowering effect.

Lastly, ezetimibe can be used to treat people with a rare inherited disorder called homozygous sitosterolaemia, where there are raised levels of plant sterols that are similar to cholesterol in the blood. In this case ezetimibe is used on its own, together with a cholesterol-lowering diet.

If you are taking Ezetimibe, you should pay more attention to it. Learning more health information, properties or suppliers aboutEzetimibe, you can access Guidechem. Guidechem chemical B2B network provides information on china and global chemical market quotation and relative chemical Information.

Variety uses of Potassium sorbate

Potassium sorbate is a chemical compound that is produced as a result of chemical reaction between potassium hydroxide and sorbic acid to produce a white, sometime yellowish crystalline powder. It is slightly acidic in nature with a ph of about 6.5. When mixed in water it forms a weak acids solution of sorbic acid.

Potassium sorbate is produced industrially by neutralizing sorbic acid with potassium hydroxide. The precursor sorbic acid is produced in a two-step process via the condensation of crotonaldehyde and ketene.

Potassium sorbate(CAS NO:24634-61-5) is a synthetic compound that is used for a variety of commercial and domestic uses, for example in the baking industry as an alternative to yeast. In addition it is also used in other industries like dried meat, cheese, apple cider and other products. The primary use of potassium sorbate is to increase the shelf life of various commercial products without causing any alteration in the taste, smell or color of the food.

Potassium sorbate is found in many food products, especially those which are meant to be stored and eaten at room temperature. This helps to ward off particles such as mold or fungus that can cause foods to spoil or make people sick. Baked goods, processed fruits and vegetables or dairy products frequently contain this product.

Personal hygiene or beauty products will also use potassium sorbate in their solutions. Shampoo, lotion, cream-based concealers and other liquid products will often contain preservatives to prevent the products spoiling or breaking down as they sit on the shelf or in room temperature storage for long periods of time.

Winemakers will also use potassium sorbate(CAS NO:24634-61-5) as part of the fermentation process so that the wine can develop without yeast that would alter the flavor by devouring the sugar content of the berries. Many waxed wrappings or coatings on foods will also contain potassium sorbate as a way to increase preservative levels without altering the recipe of the food.

Sealants, glosses and industrial coatings will often use potassium sorbate as well. This will help prevent the seal from breaking down over time and will help preserve the materials underneath. If the gloss is used on an organic material such as wood, it will prevent mold, fungus or yeast from attaching to the surface and causing damage.

Potassium sorbate is also used for a variety of industrial processes like in pain industry, rubber and plastic industry and other commercial and synthetic manufacturing units.

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2014年2月17日星期一

Side effects of DL-Phenylalanine

DL-phenylalanine is a combination of the essential amino acid L-phenylalanine and the additional stereoisomer D-phenylalanine. These chemicals have been shown to have an effect on mood. They are shown to elevate mood and can thus be used in the treatment of depression. DL-phenylalanine supplements may also increase the ability to concentrate.

It is an important precursor in the creation of many of the neurotransmitters used within the brain. L-phenylalanine is converted within the body into L-tyrosine, another important amino acid. It is used in the creation of L-dihydroxyphenylalanine, which is then converted into dopamine.

DL-phenylalanine has been studied as a substance with both analgesic and anti-depressant properties. A study from the Brampton Brain Clinic suggests that DL-phenylalanine improves the action of other painkillers by increasing activity in the endogenous analgesia system. 

Disabled World notes that DL-phenylalanine(CAS NO:150-30-1) has been shown to be particularly effective in patients who suffer from chronic pain due to conditions like arthritis. Another study led by H. Beckmann demonstrated that DL-phenylalanine worked as well as another common treatment in the reduction of depression symptoms, which has been linked in other studies to its role in the production of neurotransmitters.

Because of the potential for side effects and interactions with medications, you should only take dietary supplements under the supervision of a knowledgeable health care provider.

DL-Phenylalanine is possible safe for most people, even in amounts needed as medicine.There is insufficient reliable information available about the safety of DL-Phenylalanine.

A deficiency in DL-Phenylalanine is often evident when one exhibits signs of depression and fatigue. This may be due to the body's use of phenylalanine to produce the amino acid tyrosine, which in turn produces dopamine, norepinephrine and other chemicals that regulate mood and adrenaline. Thus, many believe that one of the most significant phenylalanine side effects is its ability to regulate mood and help combat depression.

DL-Phenylalanineside(CAS NO:150-30-1) effects can be as damaging as they are often beneficial. One of the most frightening side effects occurs in people who suffer from phenylketonuria, a disorder in which the afflicted individual is unable to produce the enzyme needed to metabolize phenylalanine. Left untreated, PKU can cause seizures and brain damage. Abnormalities from PKU are so feared that it is standard for most babies to be checked for this disorder within the first few days of life.

If you need take DL-Phenylalanineside, you should pay more attention to it. Learning more health information, properties or suppliers about DL-Phenylalanineside, you can access Guidechem. Guidechem chemical B2B network provides information on china and global chemical market quotation and relative chemical Information.

2014年2月16日星期日

Knowledge about the uses of Dioctyl phthalate

Dioctyl phthalate is an organic compound with the formula C24H38O4. It is the most common of the class of phthalate plasticizers, accounting for an almost 54% market share in 2010. It is the diester of phthalic acid and the branched-chain 2-ethylhexanol. This colourless viscous liquid is soluble in oil, but not in water, with CAS Registry Number: 117-84-0. 

Dioctyl phthalate is one of the most important plasticizer, mainly used in the processing of PVC resin and high polymers such as chemical resin, acetic acid resin, ABS resin, rubber and in the production of lacquer, dyestuff and dispersant. It is also used as a hydraulic and dielectric fluid in capacitors and as a solvent in lightsticks.

Dioctyl phthalate can be used as a softening agent , such as to make the product easier to rebound and harder to undergo form change under pressure, without affecting of the plastics. DOP possesses its good plasticizing properties thanks to the ability to make the long polimers molecules to slide against one another.

It is extensively used in processing polyvinyl choride and ethylcellulose resins to produce plastic film, imitation leather, electric wire, cable wearer, sheet, planet, mould plastic products and used in nitrocellulose paints. It has the applications in the industry of automotive, building and construction material, flooring, medical device. 

Dioctyl phthalate(CAS NO:117-84-0) has been used as a plasticiser in medical devices such as intravenous tubing and bags, catheters, nasogastric tubes, dialysis bags and tubing, and blood bags and transfusion tubing, and air tubes. For this reason, concern has been expressed about leachates transported into the patient, especially for those requiring extensive infusions, e.g. newborns in intensive care nursery settings, hemophiliacs, and kidney dialysis patients.

The American Academy of Pediatrics has advocated not to use medical devices that can leach Dioctyl phthalate into patients and, instead, to resort to Dioctyl phthalate-free alternatives. 

In July 2002, the U.S. FDA issued a Public Health Notification on Dioctyl phthalate, stating in part, "We recommend considering such alternatives when these high-risk procedures are to be performed on male neonates, pregnant women who are carrying male fetuses, and peripubertal males" noting that the alternatives were to look for non-Dioctyl phthalate exposure solutions; they mention a database of alternatives.

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2014年2月13日星期四

The basic functions of Isopropyl myristate

Isopropyl myristate is an oily liquid that is readily absorbed by the skin and is used as a base for relatively nongreasy creams and ointments. It also acts as a solvent for many medications that need to be applied to the skin. Isopropyl myristate is an ingredient or base of several emollient skin preparations used for treating dry skin conditions. 

Isopropyl myristate is a colourless to pale yellow or odourless liquid with Molecular Formula C17H34O2, Molecular Weight:270.45, and CAS Registry Number:110-27-0. It is insoluble, stable, combustible and incompatible with strong oxidizing agents.

Isopropyl myristate is found in several everyday beauty products and is generally considered safe for consumer use. Despite its popularity with manufacturers, some side effects have been reported. It is generally safe, although some people with skin conditions may wish to avoid products containing it.

Isopropyl Myristate(CAS NO:110-27-0) is used in cosmetic and topical medicinal preparations where good absorption through the skin is desired. It is also used as a pesticide-free treatment against head lice which works by dissolving the wax that covers the exoskeleton of head lice, killing them by dehydration. 

A unique characteristic of Isopropyl Myristate is its ability to reduce the greasy feel caused by the high oil content of other ingredients in a product. This synthetic oil is often added to beauty products to give them a slicker, sheer feel rather than an oily one. There are many cosmetic ingredients similar in function to this chemical, including Ethylhexyl Stearate, Isocetyl Stearate, Isopropyl Isostearate, and Myristyl Myristate.

Isopropyl Myristate is a synthetic oil used as an emollient, thickening agent, or lubricant in beauty products. Composed of of Isopropyl Alcohol and Myristic Acid, Isopropyl Myristate is a popular cosmetic and pharmaceutical ingredient. It is most often used an an additive in aftershaves, shampoos, bath oils, antiperspirants, deodorants, oral hygiene products, and various creams and lotions.

Isopropyl Myristate is easily absorbed by the skin, ensuring quick penetration of a formula's ingredients. It is so deeply penetrating that it is also an ingredient in a multi-purpose rust remover, Liquid Wrench. Though it is an effective emollient and valuable absorption carrier, repeated use of products with this ingredient may lead to clogged pores. In more than 5% of formulations, it can cause skin irritation; for this reason, it is considered a comedogenic and is aggravating to acne.

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2014年2月12日星期三

Help you find Cyclopropanecarboxylic acid

Cyclopropanecarboxylic acid is a kind of clear liquids, also known as Cyclopropanecarboxylicacid with Molecular Formula: C4H6O2 and Molecular Weight:86.09. It is miscible, stable under normal temperatures and pressures. The EINECS is 217-162-5, CAS Registry Number is 1759-53-1.

Cyclopropanecarboxylic acid is used as an intermediate for agrochemical, pharmaceuticals, and other organic synthesis such as for the applications for electronics chemicals, polymer additives, coatings, adhesives, surfactants, and other applications.

When you handing Cyclopropanecarboxylic acid: Avoid inhalation of vapour or mist. Keep away from sources of ignition - No smoking. Take measures to prevent the build up of electrostatic charge. When you storage: Store it in a cool, dry place. Store in a tightly closed container.Store at 2-8 C.

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1.Hangzhou Dayangchem Co., Ltd.
Updatetime:Feb 12 2014
DetailDesc:Cyclopropanecarboxylic acid
Tel:86-571-88938639
Address:B/2601 Fuli Building, 328# WenEr Rd. Hangzhou City 310012 China

2.AFINE CHEMICALS LIMITED
Updatetime:Feb 11 2014
Min. Order:1/Gram Supply Ability:10 Month/Metric Ton
DetailDesc:Cyclopropyl Carboxylic Acid    Tel:86-571-85232161
Address:6th Floor, Block C, 7th Building, Xigang Xinjie, Xihu Industrial Park, Sandun Town, Hangzhou, China

3.AOPHARM
Cyclopropanecarboxylic acid
Updatetime:Feb 12 2014
Purity:99% DetailDesc:Colorless or light yellow liquid
Tel:86-311-66600578
Address:C-2103 Wonder Business Square, 15 Yuhua West Rd.

4.Shanghai Dell Chemical Co.Ltd
Cyclopropanecarboxylicacid(CAS NO: 1759-53-1)
Updatetime:Feb 08 2014
Purity:NLT99% Min. Order:1/Kilogram Supply Ability:100 Year/Metric Ton
DetailDesc:Shanghai Dell Chemical Co.Ltd. is specialized in trading and developing active pharmaceutical ingredients, intermediates, API, and custom synthesis according to client’s requirements.
Tel:86-21-51950635
Address:Nianjiabang Rd, Pudong, Shanghai

5.Capot Chemical Co., Ltd.
Cyclopropanecarboxylic acid
Updatetime:Jan 27 2014
Purity:98% Min. Order:1/Kilogram Supply Ability:up to kgs Month/Kilogram
DetailDesc:86.09,C4H6O2
Tel:86-571-85586718
Address:Joinhands Science Park, No.4028,Nanhuan Road

6.Atomax Chemicals Co.,Ltd
Cyclopropanecarboxylicacid
Updatetime:Dec 11 2013
Purity:95%+ Min. Order:mg/g/Gram  Supply Ability:kg/T Month/Gram
DetailDesc:We are a leading global supplier and manufacturer of chiral chemicals, amino acids, aromatic and pyridine halogens, natural extracts and pharmaceutical raw materials. Those chemicals are widely used in the pharmaceutical and fine chemical industries and in research laboratories.
Tel:86-755-33239182
Address:Huiji302 Hutingju Sanwei Xixiang SHENZHEN 518126, China

7.Andexin industrial Co.,Limited
Cyclopropyl Carboxylic Acid
Updatetime:Feb 11 2014
Min. Order:1/Gram  Supply Ability:10 Month/Metric Ton
DetailDesc:Cyclopropyl Carboxylic Acid
Tel:86-411-39074598
Address:No.98,Shengli road,,Jinzhou district

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