Topiramate (brand name Topamax) is an anticonvulsant (antiepilepsy) drug. It was most recently approved for weight loss by the FDA in combination with phentermine. It has been used off-label for this purpose before FDA approval was obtained. It was originally produced by Ortho-McNeil Neurologics and Noramco, Inc., both divisions of the Johnson & Johnson Corporation. It was also recently approved in a combination medication used for weight loss in late 2012.
Topiramate(CAS NO.:97240-79-4) is used alone or with other medications to prevent and control seizures (epilepsy). This medication is also used to prevent migraine headaches and decrease how often you get them. Topiramate will not treat a migraine headache once it occurs. If you get a migraine headache, treat it as directed by your doctor (such as by taking pain medication, lying down in a dark room).
So how is the Comparatively Effective of Topiramate?
Two of the most important things to know when deciding on which med is the best for a particular condition: how likely is it to work and how long will it take.
The odds of a med working for a particular condition and how long it generally takes to work should be fairly easy to nail down, and not need to be summed up by the Internet shorthand YMMV (Your Mileage May Vary). Aside from it being hard enough to get an accurate diagnosis when brain cooties are involved, why is it so difficult to figure out if Topiramate is right for you and how long it will take for you to know that?
Because no one is quite sure exactly what causes various conditions. Which is further complicated when everything is a spectrum disorder. And they’re never really sure about how Topiramate works in the first place. Plus, if you have more than one condition for which you’re taking one or more medications to treat, things get really complicated. None of which is helped by studies that produce contradictory results, if they aren’t questionable in the first place.
Always remember: if your symptoms suddenly get a lot worse, call your doctor immediately. Any drug that makes your symptoms worse is a drug you probably need to stop taking as soon as possible.
How Long Until Topiramate Starts Working?
Anywhere from one day (don’t get your hopes up, but it happens) to a month. Three months is the longest wait time given, but unless you’re desperate (i.e. nothing else worked) you shouldn’t wait that long if Topiramate has done nothing for you.
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Chemical Name: Accelerator (DM)
Synonyms: Dibenzothiazole Disulfide , MBTS
Molecular Formula: C14H8N2S4
Molecular weight: 332.50
Technical specification: GB/T11408-2003
CAS No.: 120-78-5
Properties
Accelerator (DM) is a kind of white or light yellow powder with slight bitter taste, Density is 1.45-1.54, it is soluble in chloroform, partly soluble in benzene, ethanol, carbon tetrachloride, insoluble in gasoline, water and ethyl ethanol, and stable under storing conditions.
Application
Accelerator (DM) is an accelerator of NR and SR. It ahs level and middle cure rate and higher vulcanization temperature. It operates safely, disperses easily and does not contaminate. Accelerator (DM) works as plasticizer and delayed action activator in polychoroprene.
Accelerator (DM) gives flat, moderately fast cures in NR, IR, SBR, NBR, EPDM, IIR. It is also used in a wide range of general purpose rubber. Also can be used alone as delayed action accelerator, normally with accelerators of guanidines & thiurams. It is mainly used in manufacture of tires, tubes, shoes, rubber cloth and other technical rubber goods, especially those special-shaped products demanding high intensity. Exhibits better scorch safety than MBT, non-staining/ non-discoloring in white stocks. However, because of the bitterness of the product after vulcanization, it is not recommended to apply it to beverage and food containers. Accelerator (DM) can also be used as a plasticiser/ retarder in CR.
Accident release measure
Personal precautions, protective equipment and emergency procedures
Wear respiratory protection. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust.
Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let Accelerator (DM) enter drains. Discharge into the environment must be avoided.
Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Do not flush with water. Keep in suitable, closed containers for disposal.
Storage
Accelerator (DM) should be stored in the dry and cooling place with good ventilation, avoiding exposure of the packaged product to direct sunlight. Accelerator (DM) with pallet should not be stacked. Stacking of palletized material or temperature of above 35℃ can cause unusual compacted product. The validity of Accelerator (DM) is 2 years.
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Bromoethane is a colorless liquid with a vapor heavier than air. It reacts vigorously with oxidizing agents including air and strong alkalis. It is a chemical compound of the haloalkanes group. It is abbreviated by chemists as EtBr. This volatile compound has an ether-like odour. It is soluble in Dichloromethane and Methanol. We can also call it ethyl bromide, Bromoethane or Bromoethane Ethyl bromide.The Molecular Formula is C2H5Br, Molecular Weight is 108.97, and CAS NO. is 74-96-4.
It is normally used in sealed vessels. Its main use is an ethylating agent in chemical synthesis. In organic synthesis, Bromoethane is the synthetic equivalent of the ethyl carbocation (Et+) synthon. In reality, such a cation is not actually formed. For example, carboxylates salts are converted to ethyl esters, carbanions to ethylated derivatives, thiourea into ethylisothiouronium salts, and amines into ethylamines.
Halocarbons in general are potentially dangerous alkylating agents. Bromides are better alkylating agents than chlorides, thus exposure to Bromoethane should be minimized. Bromoethane is classified by the State of California as carcinogenic and a reproductive toxin.
So how to treat the accidental release of Bromoethane?
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid breathing vapors, mist or gas. Ensure adequate ventilation.
Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas.
Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let Bromoethane enter drains.
Methods and materials for containment and cleaning up
Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations (see section 13).
What should we be careful when we handing or storage Bromoethane?
Precautions for safe handling
Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge.
Conditions for safe storage, including any incompatibilities
Store Bromoethane in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Bromoethane is sensitive to light . Refrigerate before opening. Over time, pressure may increase causing containers to burst Handle and open container with care.
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2-Mercaptobenzimidazole is a kind of important Preparation Products And Raw materials, it is also known as 2-Mmbi;nocracmmb;VANOX MTI;vulkanoxmb2. The molecular formula is C8H8N2S, molecular weight is 164.23, and the CAS NO. is 583-39-1.
2-Mercaptobenzimidazole is white or light yellow crystalline powder, with bitter taste, the density is 1.42±0.02, it is soluble in ethanol, acetone and ethyl acetate, sparingly soluble in petroleum ether and dichloromethane, insoluble in carbon tetrachloride, benzene and water, non-toxic.
Used as Non-discoloring rubber antioxidant, 2-Mercaptobenzimidazole is mainly used in transparent, light or bright-colored rubber products, foam latex, electric cable (0.5%), rubber accelerator stabilizer (0.5-1.5%), thermal stabilizer in natural rubber or butadiene rubber (1-2%). It is not suitable for food-contact rubber products.Premium grade can be used as pharmaceutical intermediate.
Now we have know the basic information of 2-Mercaptobenzimidazole, but most chemicals have the risk to our body health, so does 2-Mercaptobenzimidazole. We should not only know what is 2-Mercaptobenzimidazole, but also get the knowledge about how to deal with the risk of 2-Mercaptobenzimidazole. So let me show you the knowledge.
1. FIRST AID MEASURES
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing give artificial respiration Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
2. FIRE-FIGHTING MEASURES
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special protective equipment for fire-fighters
Wear self contained breathing apparatus for fire fighting if necessary.
3. ACCIDENTAL RELEASE MEASURES
Personal precautions
Use personal protective equipment. Avoid dust formation. Avoid breathing dust. Ensure adequate ventilation.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Keep 2-Mercaptobenzimidazole in suitable, closed containers for disposal.
4. HANDLING AND STORAGE
Precautions for safe handling
Avoid 2-Mercaptobenzimidazole contact with skin and eyes. Avoid formation of dust and aerosols.
Provide appropriate exhaust ventilation at places where dust is formed. Normal measures for preventive fire protection.
Conditions for safe storage
Store 2-Mercaptobenzimidazole in cool place. Keep container tightly closed in a dry and well-ventilated place.
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Exposure controls of Veratraldehyde
Appropriate engineering controls
Handle Veratraldehyde in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Personal protective equipment
Eye/face protection
Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle Veratraldehyde(CAS NO.:120-14-9 ) with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
Body Protection
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle respirator.For higher level protection use type OV/AG/P99 (US) or type ABEK-P2 (EU EN 143) respirator cartridges.Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU)
The above information about Veratraldehyde is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information this document is based on the resent state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product.
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Appropriate engineering controls
Handle Diethanolamine in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Personal protective equipment
Eye/face protection
Tightly fitting safety goggles. Faceshield (8-inch minimum). Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle Diethanolamine(CAS NO.:111-42-2) with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
Immersion protection of Diethanolamine
Material: Nature latex/chloroprene
Minimum layer thickness: 0,6 mm
Break through time: > 480 min
Material tested:Lapren? (Anonymous Z677558, Size M)
Splash protection of Diethanolamine
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: > 30 min
Material tested:Dermatril? (Anonymous Z677272, Size M)
data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 873000, e-mail sales@kcl.de,
test method: EN374
If used in solution, or mixed with other substances, and under conditions which differ from EN 374,contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an Industrial Hygienist familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
Body Protection
Complete suit protecting against Diethanolamine, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection of Diethanolamine
Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
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Product Name: Cefuroxime Sodium for Injection
Ingredient: The main ingredient is Cefuroxime sodium.
Molecular formula: C16H15N4NaO8S
Molecular Weight: 446.37
CAS NO: 56238-63-2
Properties: This product is a kind of white to light yellow powder or crystalline powder.
Cefuroxime sodium is an antibiotic used to treat a wide variety of bacterial infections. It may also be used before and during certain surgeries to help prevent infection. This medication is known as a cephalosporin antibiotic. It works by stopping the growth of bacteria.
Cefuroxime sodium is an antibiotic Utilized to Deal with a Broad Wide range of bacterial Diseases. It May possibly also be Utilized Prior to and Throughout Specific surgeries to Support Avoid Disease. This Medicine is Acknowledged as a cephalosporin antibiotic. It Operates by stopping the Development of bacteria. Cefuroxime sodium is Offered by injection into a muscle or vein as directed by your Medical doctor. The dosage is Dependent on your Health Treatment Problem and response to Treatment.
Cefuroxime sodium is given by injection into a muscle or vein as directed by your doctor. The dosage is based on your medical condition and response to therapy.
If you are giving this medication to yourself at home, learn all preparation and usage instructions from your health care professional. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard medical supplies safely.
Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, use this drug at evenly spaced intervals.
Continue to use Cefuroxime sodium until the full prescribed treatment period is finished, even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a return of the infection. Tell your doctor if your condition persists or worsens.
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: trouble breathing, seizures.
For the best possible benefit, it is important to receive each scheduled dose of Cefuroxime sodium as directed. If you miss a dose, contact your doctor or pharmacist immediately to establish a new dosing schedule. Do not double the dose to catch up. Laboratory and/or medical tests (e.g., complete blood count) may be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.
Consult the package instructions or your pharmacist for other storage details. Keep Cefuroxime sodium away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
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