Let’s learn something about D(-)-Salicin

D(-)-Salicin is an anti-inflammatory agent that is produced from willow bark.It is also found in castoreum, which was used as an analgesic, anti-inflammatory, and antipyretic. The activity of castoreum has been credited to the accumulation of this chemical from willow trees in the beaver's diet, which is transformed to it and has an action very similar to aspirin.

Firstly, let me show you how the D(-)-Salicin works as Aspirin:

In trying to determine why D(-)-Salicin(CAS NO:138-52-3) was so effective for pain relief and reducing inflammation, pharmacists and chemists experimented with various compounds and willow bark derivatives. In 1853, a French chemist named Charles Gerhardt, attempting to make it more user-friendly, buffered it with sodium and came up with it. He had no desire to market the palatable end product and abandoned his research. It was not until 1899 that a chemist working for the German firm Bayer rediscovered Gerhardt's work, refined it and convinced his company to market it. Bayer subsequently obtained a patent on a pain reliever they called "aspirin."

Then, the other usages of D(-)-Salicin:

While originally used in a variety of pain medications, D(-)-Salicin today is more commonly used to treat skin ailments like acne, psoriasis, calluses, dandruff and warts. It speeds up the process by which the skin sheds cells, keeping pores from clogging and allowing new cells to grow. It is also used in compounds for such diverse products as sunburn cream and to make salicylanilide, which is used as a fungicide to prevent mildew. The unrefined acid is used in large amounts to make certain types of dyes. It is also the chief element in synthetic oil of wintergreen.

At last, let’s talk about the caution of D(-)-Salicin:

Many acne treatments are based on D(-)-Salicin and have been proven to be effective. They come in lotions, creams, gels and treated pads. However, sufferers should pick one remedy and not apply both pads and gels, for instance, as it has a pronounced drying effect on the skin. This could lead to other problems while not making the acne go away any faster. And, even with the buffering effect of compounds used to make it more digestible, many people are still quite sensitive to its effects.

D(-)-Salicin in blood thinning, lowering production of two enzymes, prostaglandins and thromboxanes, which reduces inflammation and the potential of platelets to stick to one another, by acting as a natural oil cleanser to wipe up the sticky and greasy layer on platelet surfaces, lessening risk of blood clots, heart attacks and strokes. In addition, salicylates reduce additional tissue damage after coronary artery disease or heart attacks, as the blood thinner properties allow for better bloodflow through clogged arteries, while possibly reducing risk of cancer as angiogenesis of cancerous cells is associated with chronic inflammation.

Mild side effects are standard, with rare occurrences of nausea, vomiting, rash, dizziness and breathing problems. Overdose from high quantities of D(-)-Salicin can be toxic, damaging kidneys, stomach causing ulcers, diarrhea, bleeding or digestive discomfort. Some people may be allergic, or sensitive to salicylates, similar to reactions to aspirin. Others that are advised against taking D(-)-Salicin are those with asthma, diabetes, gout, gastritis, hemophilia, stomach ulcers, children under 16, pregnant and breastfeeding women.

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You should learn more about D(-)-Salicin

White willow bark is the original source of D(-)-Salicin, a weaker forerunner of aspirin. Through the ages, long before the discovery of its constituent D(-)-Salicin, white willow bark was used to combat many painful conditions, including rheumatism, headache, neuralgia, arthritis, gout, and angina.

D(-)-Salicin (C13H18O7) is an alcoholic beta-glycoside which contains D-glucose. It is an anti-inflammatory which is produced from all willow barks.D(-)-Salicin(CAS NO.:138-52-3) is closely related chemically to aspirin and has a very similar action in the human body. 

When consumed, D(-)-Salicin is metabolized to salicylic acid. When ingested, D(-)-Salicin (the active glycoside in white willow) is converted into salicylic acid. (This compound has been synthesized into acetylsalicylic acid, otherwise known as aspirin.) Salicylic acid is believed to be the consitutent responsible for mediating white willows analgesic (pain relieving) effects. 

D(-)-Salicin may be used by some people that are limited to, or prefer, natural medicinal sources, as an anti-inflammatory, headache or pain relief, easing symptoms of arthritis, acne, psoriasis and warts. For reasons of safety, lower risk of side effects, and negative interaction with prescriptions such as gastrointestinal pain from ibuprofen and other non-steroidal anti-inflammatory drugs (NSAIDs). We summary the main usages of D(-)-Salicin are in fellowing:
Analgesic (pain relieving) effect. 
Antiinflammatory and Control arthritis discomforts. 
Cosmetic Application. 
Antimicrobial activity against P. acnes makes it a good candidate for skin cleansing products. 
Herbal Aspirin.

D(-)-Salicin in small amounts is found in some foods, including berries, olives, mushrooms, nuts, almonds, seeds, raisins, tomatoes, radish, chicory, green pepper, alfalfa, broccoli, spinach, sweet potato, along with some spices such as curcuma, curry, turmeric, cumin, thyme, oregano, rosemary and mustard. Higher amounts are found in some herbs such as meadowsweet, wintergreen, especially wintergreen oil, poplar tree, sweet and white birch.

Salicylates aid in blood thinning, lowering production of two enzymes, prostaglandins and thromboxanes, which reduces inflammation and the potential of platelets to stick to one another, by acting as a natural oil cleanser to wipe up the sticky and greasy layer on platelet surfaces, lessening risk of blood clots, heart attacks and strokes. In addition, salicylates reduce additional tissue damage after coronary artery disease or heart attacks, as the blood thinner properties allow for better bloodflow through clogged arteries, while possibly reducing risk of cancer as angiogenesis of cancerous cells is associated with chronic inflammation.

Mild side effects are standard, with rare occurrences of nausea, vomiting, rash, dizziness and breathing problems. Overdose from high quantities of D(-)-Salicin can be toxic, damaging kidneys, stomach causing ulcers, diarrhea, bleeding or digestive discomfort. Some people may be allergic, or sensitive to salicylates, similar to reactions to aspirin. Others that are advised against taking D(-)-Salicin are those with asthma, diabetes, gout, gastritis, hemophilia, stomach ulcers, children under 16, pregnant and breastfeeding women.

Want to learn more information about D(-)-Salicin, you can access the guidechem.com. Guidechem.com is just a place for you to look for some chemicals. Guidechem provide the most convenient conditions for the international buyers and let these leads benefit all the business people.