Bactericidal effect of Ethyl Alcohol

Ethyl Alcohol, also known as alcohol, ethanol, molecular formula is CH3CH2OH, relative molecular mass 46.07. A colorless transparent liquid, volatile, with spicy, easy burning, boiling point is 78.5 ℃, the flash point is 11.7 ℃, Ethyl Alcohol can mix with water in any ratio. Commercially available medical alcohol volume fraction is generally not less than 94.58%. CAS NO is 64-17-5.

Ethyl Alcohol is in effect disinfectant, its bactericidal effect fast, reliable sterilization effect, no toxicity to human irritation, no damage to the goods, used for skin disinfection, and disinfection of clinical medical devices.

Ethyl Alcohol is a good organic solvent, and has a strong penetration. Some disinfectant is dissolved in Ethyl Alcohol, bactericidal effect can be enhanced. Therefore, Ethyl Alcohol is also often used in the preparation of some compound disinfectant.

By experimental method to determine the molecular structure of Ethyl Alcohol which is exactly a: anhydrous Ethyl Alcohol amount, reaction order with excess sodium metal, measuring the volume of hydrogen gas, then it is converted into standard status. After further calculation, the final results are each friction Ethyl Alcohol can only generate about 0.5 friction hydrogen. Therefore, each in the Ethyl Alcohol molecule, only one hydrogen atom is sodium replacement. Then, in the Ethyl Alcohol molecule atomic arrangement is the only right is in line with the experimental results.

Bactericidal effect

Ethyl Alcohol is the most common, also the most familiar disinfectant, people from childhood vaccination before wipe with alcohol cotton ball for the skin, just know it is for disinfection, and sweet wine is out of the alcohol.

Ethyl Alcohol can disinfect bacterial, following is the mechanism of action:

(1) To make the protein denatured Ethyl Alcohol in the role of bacterial cells first to dehydration, alcohol molecules to enter the chain link protein molecules, denatures proteins precipitate; this effect is stronger in the 70% content.

(2) Damage bacterial cell wall permeability Ethyl Alcohol has a strong role, 60%~85% Ethyl Alcohol more easily penetrate into the bacteria, the bacterial cell destruction and dissolution.

(3) On microbial enzyme system damage by Ethyl Alcohol inhibition of enzyme system, especially dehydrogenase and oxidase, hinder the normal metabolism, inhibit bacterial growth and reproduction.

Ethyl Alcohol, fungi and virus multiplication of bacteria killing effect very good, study shows:

(1) Ethyl Alcohol can quickly kill bacteria propagule, but gram positive bacteria on Ethyl Alcohol resistance of gram negative bacteria is slightly stronger than. 60-75% Ethyl Alcohol, 5min can kill bacteria propagule including Bacillus, Streptococcus pyogenes; for, Neisseria gonorrhoeae, typhoid bacillus and Pseudomonas aeruginosa, can kill within 1 minutes.

(2) In higher Ethyl Alcohol volume fraction (> 80%), with the virus is very good (including small RNA virus and hepatitis B virus) virus inactivation effect, generally 3 ~ 10min. Usually, Ethyl Alcohol for lipophilic virus inactivation effect is good, but the poor effect of hydrophilic virus. About 80% of Ethyl Alcohol for fast, efficient virucide, even in presence of organics can be inactivated with hydrophilic virus resistance.

(3) Ethyl Alcohol inhibition and killing effect on fungi. Volume fraction within 70% ~ 90% range fungicidal effect; kill the fungal spores need a longer time, generally 30 ~ 60min.

(4) Ethyl Alcohol can inhibit bacterial spore germination, but can not kill the spores.

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