How does Ezetimibe work ?

Ezetimibe localises at the brush border of the small intestine, where it inhibits the absorption of cholesterol from the intestine. Specifically, it appears to bind to a critical mediator of cholesterol absorption, the Niemann-Pick C1-Like 1 protein on the gastrointestinal tract epithelial cells as well as in hepatocytes.

Ezetimibe is used along with a low cholesterol/low fat diet and exercise to help lower cholesterol in the blood. It may be used alone or with other drugs. Ezetimibe(CAS NO:163222-33-1) works by reducing the amount of cholesterol your body absorbs from your diet. Reducing cholesterol may help prevent strokes and heart attacks.

Side effects of Ezetimibe include gastrointestinal disturbances, headache, fatigue, myalgia; rarely arthralgia, hypersensitivity reactions (including rash, angioedema, and anaphylaxis), hepatitis; AND very rarely pancreatitis, cholelithiasis, cholecystitis, thrombocytopenia, raised creatine kinase, myopathy, and rhabdomyolysis.

But how does Ezetimibe work? In this article, I will show you it on the every usages of Ezetimibe.

Ezetrol tablets contain the active ingredient ezetimibe, which is type of medicine known as a cholesterol absorption inhibitor. It is used to lower high cholesterol levels.

Ezetimibe works by preventing cholesterol from being absorbed from the small intestine into the bloodstream. It prevents cholesterol and other plant sterols that are consumed in the diet from being absorbed into the bloodstream. It also prevents cholesterol released from the bile duct into the intestine from being reabsorbed into the bloodstream. The overall result is a reduction in cholesterol levels in the blood.

Ezetimibe may also be used on its own to lower cholesterol in people with primary hypercholesterolaemia who cannot take statins. Ezetimibe is used in conjunction with a statin and a cholesterol-lowering diet to lower cholesterol in people with inherited high cholesterol levels .

Ezetimibe(CAS NO:163222-33-1) is used to lower cholesterol in people with high cholesterol levels. It is normally used when another type of cholesterol-lowering medicine called a statin, together with a low cholesterol diet and increased exercise, has not lowered cholesterol sufficiently. Ezetimibe is added to the statin treatment because it works in a different way to statins and so it can boost their cholesterol lowering effect.

Lastly, ezetimibe can be used to treat people with a rare inherited disorder called homozygous sitosterolaemia, where there are raised levels of plant sterols that are similar to cholesterol in the blood. In this case ezetimibe is used on its own, together with a cholesterol-lowering diet.

If you are taking Ezetimibe, you should pay more attention to it. Learning more health information, properties or suppliers aboutEzetimibe, you can access Guidechem. Guidechem chemical B2B network provides information on china and global chemical market quotation and relative chemical Information.