Knowledge about the uses of Dioctyl phthalate

Dioctyl phthalate is an organic compound with the formula C24H38O4. It is the most common of the class of phthalate plasticizers, accounting for an almost 54% market share in 2010. It is the diester of phthalic acid and the branched-chain 2-ethylhexanol. This colourless viscous liquid is soluble in oil, but not in water, with CAS Registry Number: 117-84-0. 

Dioctyl phthalate is one of the most important plasticizer, mainly used in the processing of PVC resin and high polymers such as chemical resin, acetic acid resin, ABS resin, rubber and in the production of lacquer, dyestuff and dispersant. It is also used as a hydraulic and dielectric fluid in capacitors and as a solvent in lightsticks.

Dioctyl phthalate can be used as a softening agent , such as to make the product easier to rebound and harder to undergo form change under pressure, without affecting of the plastics. DOP possesses its good plasticizing properties thanks to the ability to make the long polimers molecules to slide against one another.

It is extensively used in processing polyvinyl choride and ethylcellulose resins to produce plastic film, imitation leather, electric wire, cable wearer, sheet, planet, mould plastic products and used in nitrocellulose paints. It has the applications in the industry of automotive, building and construction material, flooring, medical device. 

Dioctyl phthalate(CAS NO:117-84-0) has been used as a plasticiser in medical devices such as intravenous tubing and bags, catheters, nasogastric tubes, dialysis bags and tubing, and blood bags and transfusion tubing, and air tubes. For this reason, concern has been expressed about leachates transported into the patient, especially for those requiring extensive infusions, e.g. newborns in intensive care nursery settings, hemophiliacs, and kidney dialysis patients.

The American Academy of Pediatrics has advocated not to use medical devices that can leach Dioctyl phthalate into patients and, instead, to resort to Dioctyl phthalate-free alternatives. 

In July 2002, the U.S. FDA issued a Public Health Notification on Dioctyl phthalate, stating in part, "We recommend considering such alternatives when these high-risk procedures are to be performed on male neonates, pregnant women who are carrying male fetuses, and peripubertal males" noting that the alternatives were to look for non-Dioctyl phthalate exposure solutions; they mention a database of alternatives.

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