Learning some safe information about Phenyl ether

Phenyl ether is a kind of clear pale yellowish liquid after melting, it is insoluble,used in organic synthesis. The Molecular Formula is C12H10O, Molecular Weight is 170.21. Melting point: -30C ,Boiling point: 172 C, Refractive index: 1.507(20C), Flash point: 63 C. The CAS Registry Number of Phenyl ether is 101-84-8.

It can be used in dyeing synthetic fibers, both as a dye solubilizer and as a dye carrier. Ethylene glycol phenyl ether can also be used in paints and varnishes, soaps, cosmetics, perfumes, and cleaning products. It may cause moderate irritation or moderate corneal injury,

Here are some safe information about Phenyl ether(CAS NO: 101-84-8) you may need to know. Eye contact with ethylene glycol phenyl ether may cause moderate irritation and corneal injury. 

Prolonged skin exposure is unlikely to cause significant irritation. A more severe response may result on covered skin (under clothing, gloves). Prolonged skin contact is unlikely to result in absorption of harmful amounts. However, repeated skin contact may result in absorption of harmful amounts. 

In animal studies, excessive exposure caused hemolysis (breakage of red blood cells) and secondary effects to the kidneys and liver. Hemolysis impairs the blood's ability to transport oxygen and excessive exposure to ethylene glycol phenyl ether can aggravate preexisting diseases of the kidneys, liver or blood (like anemia). However, human red blood cells have been shown to be significantly less susceptible to hemolysis than those of the test animals. 

At room temperature, vapor exposure is minimal because of this material’s low volatility. However, vapor from heated material may cause eye and nose irritation and cause drowsiness.  Ethylene glycol phenyl ether has a low toxicity if swallowed. Small amounts swallowed incidental  to normal handling operations are not likely to cause injury. However, swallowing larger amounts  may cause injury. 

In animal studies, effects from repeated exposure have been reported on the red blood cells, kidney, liver, thyroid, and respiratory tract. Ethylene glycol phenyl ether did not cause birth defects or other effects in the fetus, even at doses that caused toxic effects in the mother. Repeated exposures had no effect on reproductive organs. In vitro genetic toxicity and animal genetic toxicity studies were both negative.

Ethylene glycol phenyl ether is readily biodegradable, and its potential for bioconcentration is low. Its potential for mobility in soil is high. It is practically nontoxic to aquatic organisms. 

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