2013年12月30日星期一

SUPPLY: 5-Amino-1H-tetrazole hydrate

Here are some hot suppliers of 5-Amino-1H-tetrazole hydrate in guidechem, if you need this chemical,you can contact them, I will show you the phone number and addresss of the suppliers. 

1.Capot Chemical Co., Ltd.
Updatetime:Dec 30 2013
Purity:98% Min. Order:1/Kilogram Supply Ability:up to kgs Month/Kilogram
DetailDesc:85.07,CH3N5
Tel:86-571-85586718
Address:Joinhands Science Park, No.4028,Nanhuan Road,

2.AOPHARM
5-Amino-1H-tetrazole hydrate(CAS NO: 4418-61-5)
Updatetime:Dec 30 2013
Purity:99%
DetailDesc:off-white solid
Tel:86-311-66600578
Address:C-2103 Wonder Business Square, 15 Yuhua West Rd.

3.Hangzhou Dayangchem Co., Ltd.
Updatetime:Dec 30 2013
DetailDesc:5-Aminoterazole
Tel:86-571-88938639
Address:B/2601 Fuli Building, 328# WenEr Rd. Hangzhou City 310012 China

4.Jinan Haohua Industry Co., Ltd.
5-Amino-1H-tetrazole hydrate(CAS NO: 4418-61-5)
Updatetime:Dec 30 2013
Purity:99 Min. Order:1/Kilogram Supply Ability:100 Year/Metric Ton
DetailDesc:Haohua Industry has set up four big production bases and one R&D Center in China. Over the past years, we are engaged in the exporting business, our products have reached far to the USA, Europe, South Asia, Middle East and so on, also our company has established long term. Tel:0086-531-58773055
Address:No.59 Gongye South RD

5.Shanghai UCHEM Inc.
Updatetime:Dec 30 2013
DetailDesc:5-Amino-1H-tetrazole
Tel:086-021-61555264
Address:4th Floor,Build A,500Jianyun Road,Zhoupu,Pudong,Shanghai

6.Boc Sciences
Updatetime:Dec 20 2013
DetailDesc:5-Amino-1H-tetrazole hydrate
Tel:1-631-5046093
Address:45-16 Ramsey Road Shirley, NY 11967, USA

7.Zhejiang Kaili Industrial Co., Ltd.
Updatetime:Oct 31 2013
DetailDesc:Zhejiang Kaili Industrial Co., Ltd. is collect Science, Industrial and Trade together for a comprehensive high-tech entities. We are mainly engaged in the research, development, production and sales of APIs and pharmaceutical intermediates.
Tel:86-571-85241926
Address:Block C&D,12/F,Lantian Business Center,No.18 Moganshan Road,Hangzhou,China

8.Shanghai Pengteng Fine Chemical Co., Ltd.
Updatetime:Oct 17 2013
DetailDesc:Our company keeps the business tenet of “people first and customer esteemed”and the service principle of “superior quality, reasonable price, good faith”. We insist on the principle of win-win cooperation and would like to create brilliant future hand in hand with you!
Tel:86-15262230-560
Address:No.9, Haikou Road, Huai'an Industiral Park, Jiangsu Province, China

9.Hope Pharmaceutical Co., Ltd.
Updatetime:Oct 16 2013
Tel:86-21-12345678
Address:Lane No.36, Zhongke road 2195, Zhangjiang high-tech park, Pudong new area Shanghai, China
Introduction:Founded by a group of veterans from the US biopharmaceutical industry in 2010, P&T is now a leading Shanghai-based CRO company providing drug discovery and development services worldwide. With our technical expertise and excellent research facilities, we offer broad and integrated chemical synthesis (custom synthesis, library design and synthesis), medicinal chemistry.

10.Hebei Duoke Chemical Technology Co., Ltd
5-Amino-1H-tetrazole hydrate
Updatetime:Dec 23 2013
DetailDesc: Used as intermediate in organic synthesis, electronic cleaning agent, automobile airbag, electronic products!
Tel:86-311-89630393
Address:Hebei Shijiazhuang Qiaoxi District

11.Nanjing Chemlin Chemical Co., Ltd.
5-Amino-1H-tetrazole hydrate
Updatetime:Dec 23 2013
Purity:99%
DetailDesc:5-Aminotetrazole
Tel:86-25-83697070
Address:Rm.902 Longyin Plaza, No. 217 Zhongshan Rd.(N) Nanjing 210009,China

12.Hengnuo Chemical
Updatetime:Dec 30 2013
CAS Number : 4418-61-5 EINECS Number : 224-581-7 Molecular Formula : CH3N5 Molecular Weight : 85.07 Molecular Structure : Density : 1.711 g/cm3 Melting Point : 200-206 C Appearance : white crystals Application : organic intermediate
Tel:86-153-14486766
Address:No.148 Yangtse river road, ETDZ

Want to learn more information about 5-Amino-1H-tetrazole hydrate, you can access the guidechem.com.

2013年12月29日星期日

Learning the MSDS information of 2',6'-Dihydroxyacetophenone

Hazards Identification

Acute Health Effects
Irritating to eyes and skin on contact. Inhalation causes irritation of the lungs and respiratory system. Inflammation of the eye is characterized by redness, watering, and itching. Skin inflammation is characterized by itching, scaling, reddening, or, occasionally, blistering. Follow safe industrial hygiene practices and always wear proper protective equipment when handling this compound.

Chronic Health Effects
Repeated or prolonged exposure to 2',6'-Dihydroxyacetophenone(CAS NO:699-83-2 ) is not known to aggravate existing medical conditions. The toxicological properties of 2',6'-Dihydroxyacetophenone have not been investigated. Use appropriate procedures to prevent opportunities for direct contact with the skin or eyes and to prevent inhalation. It is Non-hazardous, Non-Toxic/Non-Flammable.

First Aid Measures of 2',6'-Dihydroxyacetophenone(CAS NO:699-83-2 )

Eye Contact: Check for and remove any contact lenses. Do not use an eye ointment. Seek medical attention.

Skin Contact: After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin with running water and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin. Cover the irritated skin with an emollient. If irritation persists, seek medical attention. Wash contaminated clothing before reusing.

Serious Skin Contact: Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek medical attention.

Inhalation: Allow the victim to rest in a well ventilated area. Seek immediate medical attention.
Serious Inhalation: Not available.

Ingestion: Do not induce vomiting. Loosen tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouth resuscitation. Seek immediate medical attention.

Serious Ingestion: Not available.

First aid measures 

Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids.
Skin:Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:Remove from exposure and move to fresh air immediately.

Handling and Storage

Precautions:
Keep 2',6'-Dihydroxyacetophenone away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the residue under a fume hood. Ground all equipment containing 2',6'-Dihydroxyacetophenone. Do not breathe dust. Wear suitable protective clothing In case of insufficient ventilation, wear suitable respiratory equipment If you feel unwell, seek medical attention and show the label when possible. Avoid contact with skin and eyes

Storage:
Keep container dry. Keep 2',6'-Dihydroxyacetophenone in a cool place. Ground all equipment containing material. Keep container tightly closed. Keep in a cool, well-ventilated place. Combustible materials should be stored away from extreme heat and away from strong oxidizing agents.

Want to learn more information about 2',6'-Dihydroxyacetophenone, you can access the guidechem.com. Guidechem chemical B2B network provides information on china and global chemical market quotation and relative chemical Information. Guidechem Chemical Network providing the most complete information of the chemical industry.

2013年12月27日星期五

Make Astragaloside IV business online

In this article, I will show you a online supply platform where you can buy or sell Astragaloside IV or any other chemicals. Here are the nearly suppliers’ informetion about Astragaloside IV (CAS NO: 84687-43-4)in guidechem.

1.shijiazhuang oufuxin import & export co. , ltd
Updatetime:Dec 26 2013
Purity:99.8%
DetailDesc: extraction method:Dynamic continuous flooding extraction, ultrasonic extraction, multi-function extraction, supercritical fluid extraction. Separation of removing impurity:Centrifugal removing impurity, membrane filtration, chromatography ingenious combination of resin purification methods, short-range molecular distillation. dry method...
Tel:86-311-69010560
Address:Shijiazhuang QiaoDongOu minsheng road 33

Shanghai Dell Chemical Co.Ltd
Astragaloside IV(CAS NO: 84687-43-4)
Updatetime:Dec 26 2013
Purity:NLT99% Min. Order:1/Kilogram Supply Ability:100 Year/Metric Ton
DetailDesc:Shanghai Dell Chemical Co.Ltd. is specialized in trading and developing active pharmaceutical ingredients, intermediates, API, and custom synthesis according to client’s requirements.
Tel:86-21-51950635
Address:Nianjiabang Rd, Pudong, Shanghai

3.AFINE CHEMICALS LIMITED
Updatetime:Dec 26 2013
Min. Order:1/Gram Supply Ability:10 Month/Metric Ton
DetailDesc:Astragaloside
Tel:86-571-85232161
Address:6th Floor, Block C, 7th Building, Xigang Xinjie, Xihu Industrial Park, Sandun Town, Hangzhou, China

4.Hangzhou Dayangchem Co., Ltd.
Updatetime:Dec 26 2013
DetailDesc:Astragaloside IV
Tel:86-571-88938639
Address:B/2601 Fuli Building, 328# WenEr Rd. Hangzhou City 310012 China

5.Atomax Chemicals Co.,Ltd
Updatetime:Dec 11 2013
Purity:95+% Supply Ability:g/kg 
DetailDesc:Atomax Chemicals Co.,Ltd a leading global supplier and manufacturer of chiral chemicals, amino acids, aromatic and pyridine halogens, natural extracts and pharmaceutical raw materials. we are a registered chemicals provider for most giant pharmaceutical company like Merck, Pfizer, Novartis, Roche, Astrazeneca, Sanofi-Aventis, etc.
Tel:86-755-33239182
Address:Huiji302 Hutingju Sanwei Xixiang SHENZHEN 518126, China

6.Shanxi Sinuote Bio-Tech Co.,Ltd
Updatetime:Dec 26 2013
Purity:Astragalus Root P.E.CAS: 84687-43-4
DetailDesc: Astragalus Root P.E. CAS: 84687-43-4 0.3%, 10%, 90%, 98% test by HPLC CAS No: 84687-43-4 Molecular Formula: C41H68O14 Molecular Mass: 784.98 2. Polysaccharides 50%, 60%, 70% astragaloside iv Astragalus Root Extract Appearance: Yellow-brown powder Tel:86-29-82507780
Address:Taiyuan Road ,Xi'an City ,China

7.Andexin industrial Co.,Limited
Updatetime:Dec 26 2013
Min. Order:1/Gram Supply Ability:10 Month/Metric Ton
DetailDesc:Astragaloside
Tel:86-411-39074598
Address:No.98,Shengli road,,Jinzhou district,

8.Changsheng International Chemical Industry Co.Ltd.
Updatetime:Dec 26 2013
Supply Ability:Success 
DetailDesc:Astragaloside IV
Tel:86-311-80955068
Address:No 98 Gongnong Street,Shijiazhuang Hebei,China

9.Boc Sciences
Astragaloside IV
Updatetime:Dec 20 2013
DetailDesc:Astragaloside IV
Tel:1-631-5046093
Address:45-16 Ramsey Road Shirley, NY 11967, USA

10.Springautumn Biological Engineering Co., Ltd.
AstragalosideIV
Updatetime:Dec 20 2013
Purity:98%
DetailDesc: Synonyms AstragalosideIV CAS RN 84687-43-4 Formula C41H68O14 Molecular Weight 784.97  Tel:86-25-84430028
Address:Room 805, No. 2, sheng li cun Road, Xuanwu District, Nanjing(Xiao-Wei Street, Nanjing Jinling biomedical science and technology industrial park)

11.chengdu king-tiger pharm-chem tech co ltd
Astragaloside IV 98%
Updatetime:Oct 24 2013
Tel:86-28-85317716
Address:No. 88 keyuan South Keyuan Road Tianfu Life Science Park C1-807

Want to learn more supply information about Astragaloside IV , you can access the guidechem.com.Guidechem.com is just a place for you to look for some chemicals. Guidechem chemical B2B network provides information on china and global chemical market quotation and relative chemical Information.

2013年12月26日星期四

4 important information about 3-fluoropyridine

1.Identification

Product Name: 3-Fluoropyridine
Synonyms:Pyridine, 3-fluoro-
Formula:C5H4FN
Molecular Weight:97.09
Beilstein/Gmelin:105702
Beilstein Reference:5-20-05-00399
EINECS:206-755-4
CAS NO: 372-47-4
Appearance:Clear yellow liquid.
Soluble:Solubility in water
Boiling Point:107

2.First Aid Measures 3-fluoropyridine(CAS NO: 372-47-4)

Ingestion: Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation:Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin:Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes:Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

3.Fire Fighting Measures about 

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Extinguishing media: Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use straight streams of water. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Suitable extinguishing media: 
For small (incipient) fires, use media such as "alcohol" foam, dry chemical, or carbon dioxide. For large fires, apply water from as far as possible. Use very large quantities (flooding) of water applied as a mist or spray; solid streams of water may be ineffective. Cool all affected containers with flooding quantities of water.
Special hazards arising from the substance or mixture: Carbon oxides, nitrogen oxides (NOx), Hydrogen fluoride
Precautions for fire-fighters: Wear self contained breathing apparatus for fire fighting if necessary. 
Further information: Use water spray to cool unopened containers.

4.Handling and Storage

Storage:
Keep 3-fluoropyridine away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store 3-fluoropyridine in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.

Handling:
Wash thoroughly after handling 3-fluoropyridine. Ground and bond containers when transferring 3-fluoropyridine. Use spark-proof tools and explosion proof equipment. Avoid 3-fluoropyridine contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid 3-fluoropyridine contact with heat, sparks and flame. Avoid ingestion and inhalation. Use with adequate ventilation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.

Want to learn more information about 3-fluoropyridine, you can access the guidechem.com.

2013年12月25日星期三

List part of MSDS information about 2,3-dichloro-5-(trifluoromethyl)pyridine

Product identifiers

Product name: 2,3-dichloro-5-(trifluoromethyl)pyridine
Product Number:366145
Brand:Anonymous
Index-No.:613-158-00-6
CAS-No.:69045-84-7

Emergency overview

Hazardous Chemical. Clear, colorless liquid. Pungent, pyridine-like odor. May cause eye irritation. LD50 for skin absorption in rabbits is between 1000-2000 mg/kg. Oral LD50 for rats is between 500-1000 mg/kg. Dow AgroSciences Industrial Hygiene Guide is 10 ppm, Skin for 2,3-Dichloro-5-Trifluoromethylpyridine. Toxic to aquatic organisms and fish.
Emergency phone number : 800-992-5994

Potential health effects

This section includes possible adverse effects, which could occur if2,3-dichloro-5-(trifluoromethyl)pyridine(CAS NO:69045-84-7) is not handled in the recommended manner.

EYE: May cause slight temporary eye irritation. Vapor may cause eye irritation experienced as mild discomfort and redness.
SKIN: Essentially nonirritating to the skin. Prolonged or widespread skin contact may result in absorption of potentially harmful amounts. The LD50 for skin absorption in rabbits is between 1000-2000 mg/kg.
INGESTION: Moderate toxicity if swallowed. The oral LD50 for rats is between 500-1000 mg/kg. Small amounts swallowed incidental to normal handling operations are not likely to cause injury; however, swallowing larger amounts may cause injury.
INHALATION: Vapor concentrations are attainable, which could be hazardous on single exposure. Vapor may cause eye irritation experienced as mild discomfort and redness. Observations in animals include convulsions.

First aid measures

EYES: Flush eyes thoroughly with water for several minutes. Remove contact lenses after initial 1-2 minutes and continue flushing for several additional minutes. If effects occur, consult a physician, preferably an ophthalmologist.
SKIN: Immediately flush skin with water while removing contaminated clothing and shoes. Get medical attention if symptoms occur. Wash clothing before reuse. Destroy contaminated articles including leather items such as shoes.
INGESTION: If swallowed, seek medical attention. Do not induce vomiting unless directed to do so by medical personnel.
INHALATION: Move person to fresh air. If not breathing, give artificial respiration. If breathing is difficult, oxygen should be administered by qualified personnel. Call a physician or transport to a medical facility.

Exposure control & personal protection

Exposure guideline(S): 2,3-Dichloro-5-Trifluoromethylpyridine: Dow AgroSciences Industrial Hygiene Guide is 10 ppm, Skin.
Engineering controls: Provide general and/or local exhaust ventilation to control airborne levels below exposure guidelines.
EYE PROTECTION: Use safety glasses. Where contact with this material is likely, chemical goggles are recommended because eye contact may cause discomfort even though it is unlikely to cause injury. If exposure causes eye discomfort, use a full-face respirator.
RESPIRATORY PROTECTION: Atmospheric levels should be maintained below the exposure guideline. When respiratory protection is required for certain operations, use a NIOSH approved air-purifying respirator. For emergency and other conditions where the exposure guideline may be greatly exceeded, use a NIOSH approved positive-pressure self-contained breathing apparatus or positive-pressure airline with auxiliary self-contained air supply.
SKIN PROTECTION: Use protective clothing chemically resistant to 2,3-dichloro-5-(trifluoromethyl)pyridine. Selection of specific items such as faceshield, gloves, boots, apron, or full body suit will depend on operation. Remove contaminated clothing immediately, wash skin area with soap and water, and launder clothing before reuse or dispose of properly.

These above are not the complete MSDS information of 2,3-dichloro-5-(trifluoromethyl)pyridine, looking for more detail information about 2,3-dichloro-5-(trifluoromethyl)pyridine, you can access to our guidechem.

2013年12月19日星期四

Talking about some questions about Chromic acid

Q1:Is there something different between potassium dichromate and chromic acid ?

Yes , they are not the same. Chromic acid can be either H2CrO4 or H2Cr2O7 or a mixture of the two. The key thing is that chromium must be in the +6 oxidation state. Chromic acid can be prepared by acidifying your potassium dichromate with sulfuric acid. This makes a good but toxic glassware cleaner. It works by oxidizing the stuff stuck to the glassware and is reduced to [Cr(H2O)6]3+ in the process. 

The problem is that chromium is an environmental toxin and the use of chromic acid(CAS NO:7738-94-5)to clean glassware has dropped off to nil. How about buying some Alconox. It's much safer and works almost as well. 

Q2:What are the dangers of chromic acid?

Chromic acid(CAS NO:7738-94-5), soln. of Chrom (VI) Oxide, CrO3 is probably the most common salt of Cr6+.  Contrary to Cr3+ which is needed by our body (in small quantity), Cr6+ is very toxic. IN long term is is a confirmed carcinogenic and mutagenic. It also cause sensitizations on some individuals. 

Spilling it on skin is bad, but I'm more concern about breathing the materail. The dust of Cr6+ is extremely corrosive to you lung tissue, causing severe irritation to mucose and upper respiratory tract. Worse, if it travels down to bronchea and ultimately alveoli, especially on going on basis, it may lead to a lung cancer and similar symptoms. 

Q3:Is there a difference between hydrogen chromate and chromic acid?

The prefixes and suffixes describe the formula of the acid. For the acid containing the most common polyatomic ion of its group simply use the first part of the polyatomic name and follow with the suffix ic. Ex. H2 SO4 Sulfuric acid  Chromate, CrO4 -2, is the most common ion of chromium and oxygen.  So H2CrO4 is chromic acid. Hydrogen chromate is the name of a compound, which contains hydrogen and the chromate ion. 
H = +1                            CrO2 = -2 
H2CrO4 is the chemical formula of Hydrogen chromate 
Chromic acid and Hydrogen chromate are 2 names for the same compound. 
Hydrogen Phosphate = H+1 + PO4 -3 = H3PO4 
Phosphoric acid = H3PO4  The same is true for H3PO4 

Q4:How much chromic acid would react with 1g ethanol if the yield is quantitative?

Figure out how many moles of ethanol you have. Then since chromic acid reacts 2 to 1 with the ethanol you know you have 2 times that many moles chromic acid. Figure out the formula weight of chromic acid, then multiply by the moles of chromic acid you have. Lets assume the formula weight for ethanol is 46 grams per mole, then since you only have 1 gram, that 1/46th of a mole.

Want to learn more information about Chromic acid, you can access the guidechem.com.  Guidechem provide the most convenient conditions for the international buyers and let these leads benefit all the business people. 

2013年12月18日星期三

Online trade : 2-Ethyl-1-hexanol

2-Ethyl-1-hexanol is a clear, colourless liquid with an odour described as sweet, floral, intense, and unpleasant. Its formula is C8H18O, and CAS NO is 104-76-7. It occurs naturally in food and is also added as flavouring to foods. This compound is formulated by petrochemical synthesis and used predominately in the production of plasticizers for PVC resins, hexyl esters, and arylates. 2-Ethyl-1-hexanol is also used in textiles and as a solvent and wetting agent. 

Almost all 2-Ethyl-1-hexano is converted into the diesters bis(2-ethylhexyl) phthalate (DEHP), a plasticizer. Because it is a fatty alcohol, its esters tend to have emollient properties. For example, the sunscreen octocrylene contains a the chemical for this purpose. It is also commonly used as a low volatility solvent. It can also be used as an octane booster when reacted with nitric acid.

In this article,I will show you some supply companies of 2-Ethyl-1-hexanol(CAS NO:104-76-7) in guidechem. Here are the company information. Guidechem is a B2B network which provide you chemical information online. 

1.Hangzhou Dayangchem Co., Ltd.

2-Ethyl-1-hexanol
Updatetime:Dec 18 2013
DetailDesc:2-Ethyl-1-hexanol
Tel:86-571-88938639
Address:B/2601 Fuli Building, 328# WenEr Rd. Hangzhou City 310012 China.

2.Shanghai Dell Chemical Co.Ltd

2-Ethylhexanol
Updatetime:Dec 17 2013
Purity:NLT99% Min. Order:1/Kilogram Supply Ability:100 Year/Metric Ton
DetailDesc:Shanghai Dell Chemical Co.Ltd. is specialized in trading and developing active pharmaceutical ingredients, intermediates, API, and custom synthesis according to client’s requirements.
Tel:86-21-51950635
Address:Nianjiabang Rd, Pudong, Shanghai

3.AFINE CHEMICALS LIMITED

2-Ethyl Hexanol (Octanol)
Updatetime:Dec 17 2013
Min. Order:1/Gram Supply Ability:10 Month/Metric Ton
DetailDesc:2-Ethyl Hexanol (Octanol)
Tel:86-571-85232161
Address:6th Floor, Block C, 7th Building, Xigang Xinjie, Xihu Industrial Park, Sandun Town, Hangzhou, China

4.Atomax Chemicals Co.,Ltd

2-Ethylhexan-1-ol
Updatetime:Dec 11 2013
Purity:95+% Supply Ability:g/kg 
DetailDesc:Atomax Chemicals Co.,Ltd a leading global supplier and manufacturer of chiral chemicals, amino acids, aromatic and pyridine halogens, natural extracts and pharmaceutical raw materials. we are a registered chemicals provider for most giant pharmaceutical company like Merck, Pfizer, Novartis, Roche, Astrazeneca, Sanofi-Aventis, etc.
Tel:86-755-33239182
Address:Huiji302 Hutingju Sanwei Xixiang SHENZHEN 518126, China

5.Jinan Haohua Industry Co., Ltd.

2-Ethylhexanol
Updatetime:Dec 18 2013
Purity:99 Min. Order:1/Kilogram Supply Ability:100 Year/Metric Ton
DetailDesc:(-2-Ethyl-1-hexanol;2-Ethyl-1-hexanol;2-Ethyl-1-hexyl alcohol;2-Ethylhexylalcohol;Conol 10WS;Ethylhexanol;G 301;NSC 9300;Iso-Octanol;
Tel:0086-531-58773055
Address:No.59 Gongye South RD

6.Wuhan Haizheng Industry & Trade Development Co. Ltd

2-Ethylhexanol
Updatetime:Dec 10 2013
Purity:98.00% Min. Order:10/Gram Supply Ability:2300 Month/Kilogram
DetailDesc: Appearance: colourless liquid Molecular Weight: 130.23 Density: 0.833 Boiling Point: 184C Melting Point: -76C Flash Point: 77C Storage Temperature: Keep away from heat, sparks, and flame. Keep away from sources of ignition. Keep container closed when not in use. 
Tel:86-27-88660577
Address:27th FL.shuian international masion Bldg.1,Heping Ave.wuhan city

Here I can only introduce you the 6 suppliers of 2-Ethylhexanol in guidechem, if you need more supply information about 2-Ethylhexanol, you can access to our guidechem.com.

2013年12月17日星期二

Online Supply information of Trimethylacetyl chloride

Trimethylacetyl chloride is a kind of important pharmaceutical intermediates, it is widely used in industry. Molecular Formula is C5H9ClO, Molecular Weight is120.58, CAS Registry Number is 3282-30-2. Guidechem is a B2B network which provide you chemical information online. It provides information on china and global chemical market quotation and relative chemical Information. In this article,I will show you some supply companies of Trimethylacetyl chloride in guidechem. Here are the company information.

1.Supplier one : Hangzhou Dayangchem Co., Ltd.

Trimethylacetyl chloride
Updatetime:Dec 17 2013
DetailDesc:Pivaloyl chloride
Tel:86-571-88938639
Address:B/2601 Fuli Building, 328# WenEr Rd. Hangzhou City 310012 China

2.Supplier two : Jinan Haohua Industry Co., Ltd.

Trimethylacetyl chloride(CAS NO: 3282-30-2)
Updatetime:Dec 17 2013
Purity:99 Min. Order:1/Kilogram Supply Ability:100 Year/Metric Ton
Tel:0086-531-58773055
Address:No.59 Gongye South RD

3.Supplier three : Fplus International Limited

Updatetime:Dec 09 2013
Purity:99% min Min. Order:5/Metric Ton Supply Ability:12000 Year/Metric Ton
DetailDesc: Pivaloyl chloride CAS No: 3282-30-2 EINECS No: 221-921-6 Molecular formula: C5H9ClO Molecular weight: 120.5774 Other names: Pivalyl chloride, trimethylacetyl chloride or 2,2-dimethyl propionyl chloride Physicochemical Properties: colorless or yellowish transparent liquid, inflamble.
Tel:852-2-6712811
Address:No.2,Unit 1008,Level 10,Landmark North,Sheung Shui,N.T.

4.Supplier four :Zouping Mingxing Fine Chemical Co,Ltd.(China)

Updatetime:Oct 05 2013
Purity:99.00%min
DetailDesc: Pivaloyl chloride Name: Pivaloyl chloride Synonyms: Trimethylacetyl chloride; 2,2-Dimethyl-propanoyl chloride CAS NO: 3282-30-2 EINECS: 221-921-6 Molecular Structure: Molecular Formula: C5H9ClO Molecular Weight: 120.58 Density: 0.979
Tel:86-136-05431940
Address:No 428 Daixi Third Road Zouping County Shandong China

5.Supplier five :Shanghai Zhongxi International Trading Co.,Ltd

Updatetime:Dec 29 2012
Purity:98%
DetailDesc:Molecular Formula: C5H9ClO Molecular Weight: 120.58 InChI: InChI=1/C5H9ClO/c1-5(2,3)4(6)7/h1-3H3 Synonyms: pivaloyl chloride; PIVALOYL CHLORIDE(PVCL); Pivaloyl chloride.
Tel:86-21-58202529
Address:No.1515,Jiaotong Rd, Shanghai 200165, China

6.Supplier six : AOPHARM

Trimethylacetyl chloride
Updatetime:Dec 17 2013
Min. Order:
DetailDesc:Pivaloyl chloride
Tel:86-311-66600578
Address:C-2103 Wonder Business Square, 15 Yuhua West Rd.

7.Supplier seven : Shanghai UCHEM Inc.

Trimethy-lacetly chloride
Updatetime:Dec 17 2013
DetailDesc:Trimethy-lacetly chloride
Tel:086-021-61555264
Address:4th Floor,Build A,500Jianyun Road,Zhoupu,Pudong,Shanghai

8.Supplier eight : Boc Sciences

Trimethylacetyl chloride
Updatetime:Nov 27 2013
DetailDesc:Trimethylacetyl chloride
Tel:1-631-5046093
Address:45-16 Ramsey Road Shirley, NY 11967, USA

9.Supplier nine: Hangzhou UNIWISE International Co.,Ltd.

Trimethylacetyl chloride
Updatetime:Oct 21 2013
Tel:+86-571-28819531
Address:E-19F, Dongqiing Building, 52 Qingchun Rd, Hangzhou, China
10.Supplier ten: lotuschem

Trimethylacetyl chloride
Updatetime:Jul 31 2013
Tel:852-29738324
Address:Rm. 907. JCD116 Wing Tuck Commercial Centre, 177-183 Wing Lok Street, Hong Kong

Here I can only introduce you the 7 suppliers of Trimethylacetyl chloride in guidechem, if you need more supply information about Trimethylacetyl chloride, you can access to our guidechem.com.

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2013年12月16日星期一

Complete side effects about Olmesartan medoxomil

Olmesartan medoxomil is a white to light yellowish-white powder or crystalline powder with a molecular weight of 558.59. It is practically insoluble in water and sparingly soluble in methanol. Formula of Olmesartan medoxomil is C29H30N6O6,CAS number is 144689-63-4 .

Olmesartan medoxomil is a prodrug that is rapidly hydrolyzed into olmesartan in the gastrointestinal tract. Olmesartan is rapidly absorbed from the gastrointestinal tract into the body, with a maximum plasma concentration of 0.22-2.1 mg/L and time to Cmax of 1.4-2.8 h following administration of olmesartan medoxomil 10-160 mg (Schwocho and Masonson 2001). For the same doses, the mean area under the concentration-time curve (AUC) was 1.6-19.9 mgh/L.

Olmesartan medoxomil(CAS NO:144689-63-4) should be used with caution in renal artery stenosis. Monitoring of plasma-potassium concentration is advised, particularly in the elderly and in patients with renal impairment; lower initial doses may be appropriate in these patients. 

It should also be used with caution in aortic or mitral valve stenosis and in hypertrophic cardiomyopathy. Those with primary aldosteronism, and Afro-Caribbean patients (particularly those with left ventricular hypertrophy), may not benefit from an Olmesartan medoxomil.

There are some side effects of Olmesartan medoxomil we should take care of.

Dizziness or lightheadedness may occur as your body adjusts to the medication. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if any of these unlikely but serious side effects occur: fainting, slow/irregular heartbeat, unusual decrease in the amount of urine.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Because clinical studies are conducted under widely varying conditions, adverse reaction rates observed in the clinical studies of a drug cannot be directly compared to rates in the clinical studies of another drug and may not reflect the rates observed in practice.

Olmesartan medoxomil has been evaluated for safety in more than 3825 patients/subjects, including more than 3275 patients treated for hypertension in controlled trials. This experience included about 900 patients treated for at least 6 months and more than 525 for at least 1 year. Treatment with Olmesartan medoxomil was well tolerated, with an incidence of adverse reactions similar to placebo. Events generally were mild, transient and had no relationship to the dose of Olmesartan medoxomil.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. Want to learn more information about Olmesartan medoxomil, you can access the guidechem.com.

2013年12月15日星期日

Study on the unknown usages of Methyl disulfide

Methyl disulfide(DMDS) is of Slightly yellow transparent liquid, there is stench flavor, melting point is at -98 DEG C, boiling point 109. 5DEG C, insoluble in water, easily soluble in acetic acid, ethanol. The molecular formula is C2H6S2, molecular weight is 94.2, and the CAS NO is 624-92-0.

Dimethyl disulfide along with dimethyl sulfide and dimethyl trisulfide have been confirmed as volatile compounds given off by the fly-attracting plant known as dead-horse arum. These flies are attracted to the odor of fetid meat, they help pollinate this plant.

Methyl disulfide(CAS NO:624-92-0) is a stable pale yellow liquid which works as an effective product in the sulfiding process because of its high sulphur content. Methyl disulfide is used as activator of hydrogen desulfurization and precuring process in refining petroleum refining; it may used as cracking, coking inhibitor in petrochemical; it also used as solvent and pesticide intermediate 

Despite its use in a wide variety of industrially important thermochemical processes, little is known about the thermal decomposition mechanism of dimethyl disulfide (DMDS). To obtain more insight, the radical decomposition mechanism of Methyl disulfide is studied theoretically and a kinetic model is developed accounting for the formation of all the decomposition products observed in the experimental studies available in literature. 

Thermochemical data and rate coefficients are obtained using the high-level CBS-QB3 composite method. Among five methods tested (BMK/6-311G(2d,d,p), MPW1PW91/6-311G(2d,d,p), G3, G3B3, and CBS-QB3), the CBS-QB3 method was found to reproduce most accurately the experimental standard enthalpies of formation for a set of 17 small organosulfur compounds and the bond dissociation energies for a set of 10 sulfur bonds. 

Enthalpies of formation were predicted within 4 kJ mol−1 while the mean absolute deviation on the bond dissociation enthalpies amounts to 7 kJ mol−1. From the theoretical study, a new reaction path is identified for the formation of carbon disulfide via dithiirane (CH2S2). 

A reaction mechanism was constructed containing 36 reactions among 25 species accounting for the formation of all the decomposition products reported in literature. High-pressure limit rate coefficients for the 36 reactions in the reaction mechanism are presented. The kinetic model is able to grasp the experimental observations. 

With the recombination of thiyl radicals treated as being in the low-pressure limit, the experimentally reported first-order rate coefficients for the decomposition of Methyl disulfide are reproduced within 1 order of magnitude, while the observed product selectivities of most compounds are reproduced satisfactory. Simulations indicate that at high conversions most of the carbon disulfide forms according to the newly identified reaction path involving the formation of dithiirane.

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2013年12月13日星期五

Study on the Environmental effects of Paclobutrazol

Paclobutrazol is a plant growth regulator belonging to the triazole chemical class (U.S.  EPA, 2007B). Paclobutrazol was first registered by U.S. EPA in 1985. At the time of preparation of this review in 2011, PBZ was undergoing registration review by U.S. EPA to determine whether it continues to meet the FIFRA standard for registration . As part of the registration review process, a summary document was issued. This document includes a factsheet describing the Environmental Fate of Paclobutrazol.

Paclobutrazol(CAS NO:76738-62-0) has been characterized as a compound with a moderate potential for mobility in soil and water environments. The summary document for registration review prepared by U.S. EPA documents that laboratory batch equilibrium studies indicated that this chemical has the capacity to be mobile under certain conditions. Studies with nine US soils ranging in texture from sand to silt loam indicated values for the soil adsorption coefficient KD in the range from 1.3 to 23.0 ml/g. 

Adsorption appeared to increase with an increase in soil organic matter content and a decrease in soil pH. In the draft assessment report prepared by the United Kingdom adsorption data for 13 soils are summarized that show KD values in the range of 0.8-21.3 ml/g with a geometric mean of 4.3 ml/g. The ketone metabolite showed on average a slightly higher affinity for adsorption to soil with KD values in the range of 2.1-13.5 with a mean of 8.0 across 6 soils.

Results from laboratory soil column leaching experiments summarized in U.S. EPA indicated low mobility in the experiments using methine-labeled Paclobutrazol(CAS NO:76738-62-0) in soils ranging in texture from sand to clay-loam. The experiments using triazole-labeled Paclobutrazol showed low mobility in columns of sand and sandy loam soils, and mobility in loamy sand and clay loam soils. In all cases, the majority (58.6-90.7%) of applied Paclobutrazol aged residue did not leach out of the upper 10 cm of the treated soil columns.

Although characterized as moderately mobile in laboratory studies, no significant movement of this chemical was detected in field studies in agricultural soils. In the orchard studies, Paclobutrazol residues (parent plus degradate) were detected at 10% or less of total applied in soils with depths of 48 inches in the California study, 24 inches in West Virginia study, and 48 inches in the Florida study. 

These depths are the maximum depths sampled at each study. No information was provided on the nature or type of soils in the summary document. The Paclobutrazol ketone metabolite was predominately detected in the subsurface soil layers, also at insignificant levels.

A scientific publication by Baris et al. (2010) provided information regarding the potential of Paclobutrazol to impact groundwater from its use on turf areas. Paclobutrazol was included in a comprehensive evaluation of water quality monitoring data and assessment. This evaluation considered water quality data for a large number of turf-related pesticides from 44 studies involving 80 golf courses in the US over a 20-year period. PBZ was found in 3/440 groundwater samples, with the highest detection at 4.2 µg/L.

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2013年12月12日星期四

New study on Mancozeb


Mancozeb is non-systemic fungicide, Organic-Dithiocarbamate group. Foliar protection of many fruits, vegetables, nuts and field crops against a wide spectrum of fungal diseases including potato blight, leaf spots, scab on apples and pears, anthracnose and rust. 

For seed treatment of rice, cotton, potatoes,safflower, sorghum, peanuts, tomatoes, flax, and cereal grains.Mancozeb(CAS NO:8018-01-7) does not induce in fungi and is therefore an essential componentof alternating spray program or of mixed formulations with systemic and other fungicides.

Polyvalence: use on more than 70 crops for the control of 400 fungal diseases of which mildews, excoriosis, black-rot, red fire, alternaria, etc. Multi-site action: making it an ideal partner for recent mono-site molecules. 

Nutrient: correction of crop deficiencies in manganese and zinc.The worldwide use mancozeb(CAS NO:8018-01-7) without danger to the environment. Because mancozeb break down rapidly in the environment. It is not harmful to beneficial insects and natural pollinators. Hence it is a useful product in integrated pest management programs. Mancozeb is a contact fungicide which remains on the treated surface of the plant.

Mancozeb is a member of the ethylene bisdithiocarbamate (EBDC) group of fungicides that also includes the related active ingredient metiram, the only other registered EBDC. A third EBDC, maneb, is no longer registered for use. 

Mancozeb and metiram are metabolized to ethylenethiourea (ETU) in the body and both degrade to ETU in the environment. Therefore, EPA has considered the aggregate or combined risks from food, water and non-occupational exposure resulting from mancozeb alone and ETU from all sources (i.e., the other EBDC fungicides) for this action. EPA's assessment of exposures and risks associated with mancozeb and ETU follows.

Mancozeb is not acutely toxic via the oral, dermal or inhalation routes of exposure. Further, mancozeb is not a skin irritant nor is it a skin sensitizer, although it does cause mild eye irritation. The findings in multiple studies demonstrate that the thyroid is a target organ for mancozeb. 

Thyroid toxicity is manifested as alternations in thyroid hormones, increased thyroid weight, and microscopic thyroid lesions (mainly thyroid follicular cell hyperplasia). These effects are due to the ETU metabolite.

Mancozeb is rapidly absorbed and eliminated in the urine. In oral rat metabolism studies with radiolabeled mancozeb and other EBDCs, an average 7.5%in vivo metabolic conversion of EBDC to ETU occurred, on a weight-to-weight basis. 

Metabolism data indicate mancozeb does not bio-accumulate. Mancozeb has been tested in a series of in vitro and in vivo genotoxicity assays, which have shown that it exhibits weak genotoxic potential.

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2013年12月11日星期三

Methyl acetoacetate companies

Methyl acetoacetate is a kind of colorless liquid, we also call it Acetoacetic acid methyl ester or Butanoic acid, 3-oxo-, methyl ester. The Molecular Formula is C5H8O3, Molecular Weight is 116.12, and CAS Registry Number is 105-45-3.

Methyl acetoacetate is stable under normal temperatures and pressures. We should store Methyl acetoacetate in a cool, dry place, and keep the container closed when not in use. Methyl acetoacetate (MAA) is a starting material for the syntheses of alpha-substituted aceto- acetic esters and cyclic compounds, e.g. pyrazole, pyrimidine and coumarin derivatives.

After introducting the basic properties of Methyl acetoacetate(CAS NO:105-45-3), I will show you some suppliers information about this chemical on Guidechem. If you need to buy this chemical, you can access to Guidechem, and contact them, I hope this information is useful for you.

Company one : Shanghai Dell Chemical Co.Ltd
Updatetime:Dec 10 2013
Purity:NLT99% Min. Order:1/Kilogram Supply Ability:100 Year/Metric Ton
DetailDesc:Shanghai Dell Chemical Co.Ltd. is specialized in trading and developing active pharmaceutical ingredients, intermediates, API, and custom synthesis according to client’s requirements.
Tel:86-21-51950635
Address:Nianjiabang Rd, Pudong, Shanghai

Company two :Jinan Haohua Industry Co., Ltd.
Updatetime:Dec 10 2013
Purity:99 Min. Order:1/Kilogram Supply Ability:100 Year/Metric Ton
DetailDesc:Acetoaceticacid, methyl ester (6CI,8CI); 3-Oxobutanoic acid methyl ester; 3-Oxobutyricacid methyl ester; Acetoacetate methyl ester; Methyl 3-oxobutanoate; Methyl3-oxobutyrate; Methyl acetoacetate; Methyl acetylacetate
Tel:0086-531-58773055
Address:No.59 Gongye South RD

Company three : Nanjing Chemlin Chemical Co., Ltd.
Updatetime:Dec 09 2013
Purity:97.00%
DetailDesc:intermediates, drug discovery
Tel:86-25-83697070
Address:Rm.902 Longyin Plaza, No. 217 Zhongshan Rd.(N) Nanjing 210009,China

Company four : Finetech Industry Limited
Methyl acetoacetate
Updatetime:Oct 06 2013
Introduction:Finetech Industry Limited specializes in the development, manufacture and marketing of Fine organic Compounds & Intermediates for the Pharmaceutical Industry. Tel:+86-(27)-87772287
Address:Guanggu Road, Wuhan, Hubei 430073

Company five : Conier Chem & Pharma Co.,Ltd.
Methyl acetoacetate
Updatetime:Aug 26 2013
Tel:+86-(23)-62922305
Address:24 South Section 1, Yihuan Road, Chengdu, Sichuan 610065,
Introduction: Conier Chem & Pharma Co.,Ltd. offers Pharmaceutical Intermediates, Fine Chemicals and APIs. We supply darifenacin, venlafaxine HCl, nebivolol, qQuetiapine, methoxyindole, 2-Methyl-5-pyrimidinemethanol and 4-phenoxypyridine. We develop comprehensive service in the field of chemical and pharmaceutical. 

Company six : Goly Chemical Co., Ltd.
Methyl acetoacetate
Updatetime:Jan 16 2013
Tel:+86-(632)-6163187
Address:Room No.6.Building21 LongXingBeiLi,ShiZhong, ZaoZhua, ShanDong 277102,
Introduction:Goly Chemical Co., Ltd. specializes in Active Pharmaceutical Ingredients, Intermediates, Specialty Chemicals, and Water Treatment Agents & Food Additives. We focus on the Special Chemicals and Fine Chemicals such as Active Pharmaceutical Ingredients Organic Intermediates Inorganic Compound Amino Acid Series Fluoro-Compound.

I can only introduct you 6 companies which supply Methyl acetoacetate in our guidechem, if you need to learn more information about Methyl acetoacetate, you can access the guidechem.com, more suppliers of any other chemicals are in this site.

2013年12月10日星期二

Take care of 2-Bromo-3-hydroxypyridine in 4 aspects

2-Bromo-3-hydroxypyridine, its systematic name is 2-bromopyridin-3-ol. It should be sealed and stored in a cool and dry place. Moreover, it should be protected from light. It is used in organic synthesis.It can be used to produce 2-bromo-3-isopropoxypyridine at the temperature of 80 C. It will need reagent K2CO3 and solvent dimethylformamide with the reaction time of 2 hours.

1.Summary of the Hazards 

When you are using 2-Bromo-3-hydroxypyridine(CAS NO:6602-32-0), please be cautious about it as the following: 2-Bromo-3-hydroxypyridine is harmful by inhalation, in contact with skin and if swallowed. It is irritating to eyes, respiratory system and skin; in case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice, when using it, you need wear suitable protective clothing and must avoid contact with eyes.

2.First Aid Measures

Eyes:
Check for and remove any contact lenses. IMMEDIATELY flush eyes with runing water for at least 15 minutes; Keeping eyelids open. COLD water may be used; DO NOT use an eye oitment. Flush eyes with running water for a minimum of 15 minutes, occasionally lifting the upper eyelids. Seek medical attention. Treat symptomatically and supportively.

Skin:
If 2-Bromo-3-hydroxypyridine(CAS NO:6602-32-0) contact with skin, wash immediately with plenty of water. Gently and thorough wash the contaminated skin with running water and non-abrasive soap; Be particularly careful to clean folds, crevices, creases and groin; COLD water may be used; Cover the irritated skin with an emollient. Seek medical attention. Treat symptomatically and supportively. Wash any contaminated clothing before reusing.

Inhalation:
If the victim is not breathing, perform artificial respiration. Loosen tight clothing such as a collar, tie, belt or waistband. If breathing is difficult, oxygen can be administered; Seek medical attention. Treat symptomatically and supportively.

Ingestion:
INDUCE VOMITING by sticking finger in throat. Lower the head so that the vomit will not reenter the mouth and throat; Loosen tight clothing such as a collar, tie, belt, or waistband. If the victim is not breathing, administer artificial respiration. Examine the lips and mouth to ascertain whether the tissues are damaged, a possible indication that the toxic material was ingested; the absence of such signs, however, is not conclusive. Seek immediate medical attention and, if possible, show the chemical label. Treat symptomatically and supportively.

3.Accidental Release Measures

In case of a spill or a leak, always shut off any sources of ignition, ventilate the area, and exercise caution. Use a shovel to put the material into a convenient waste disposal container; Finish cleaning the spill by rinsing anycontaminated surfaces with copious amounts of water; Consult federal, state, and/or local authorities for assistance on disposal.

4.Handling and Storage

Keep 2-Bromo-3-hydroxypyridine away from heat and sources of ignition. Mechanical exhaust required; When 2-Bromo-3-hydroxypyridine is not in use, tightly seal the container and store in a dry, cool place. Avoid excessive heat and light. Do not breathe 2-Bromo-3-hydroxypyridine dust; Always store 2-Bromo-3-hydroxypyridine away from incompatible compounds such as oxidizing agents.

Want to learn more information about 2-Bromo-3-hydroxypyridine, you can access the guidechem.com. Guidechem provide the most convenient conditions for the international buyers and let these leads benefit all the business people.

2013年12月9日星期一

MSDS of Indazole-3-carboxylic acid

Indazole-3-carboxylic acid is used in organic synthesis. For example: it can react with 1,4-dimethyl-[1,4]diazepan-6-ylamine to get 1H-indazole-3-carboxylic acid.This reaction needs reagent 1-ethyl-3-<3-(dimethylamino)propyl>carbodiimide hydrochloride and solvent CH2Cl2 at ambient temperature. The reaction time is 5 hours. The yield is 21%.

When you are using Indazole-3-carboxylic acid(CAS NO:4498-67-3), please be cautious about it as the following: Indazole-3-carboxylic acid is not only harmful if swallowed, but also irritating to eyes, respiratory system and skin. So people should not breathe dust. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. If you want to contact Indazole-3-carboxylic acid, you must wear suitable protective clothing, gloves and eye/face protection.

Potential Health Effects about Indazole-3-carboxylic acid(CAS NO:4498-67-3)

Eye: Causes eye irritation. 
Skin: Causes skin irritation. May be harmful if absorbed through the skin. 
Ingestion: Harmful if swallowed. May cause irritation of the digestive tract. 
Inhalation: Causes respiratory tract irritation. May be harmful if inhaled. 
Chronic: No information found. 

First Aid Measures about Indazole-3-carboxylic acid

Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.  Get medical aid. Immediately flush skin with plenty of water for at least 15 minutes while removing   
Skin: contaminated clothing and shoes. 
Ingestion: Do not induce vomiting. Get medical aid immediately. Call a poison control center. 
Inhalation:Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Get medical aid. Do not use mouth-to-mouth resuscitation if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. 
Notes to Physician: Treat symptomatically and supportively. 

Fire Fighting Measures about Indazole-3-carboxylic acid

General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. 
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. 


Handling and Storage about Indazole-3-carboxylic acid

Handling: Use with adequate ventilation. Minimize dust generation and accumulation. Do not get in eyes, on skin, or on clothing. Do not ingest or inhale. 
Storage: Store in a cool, dry place. Store in a tightly closed container.

Personal Protective Equipment 

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. 
Skin: Wear appropriate protective gloves to prevent skin exposure to Indazole-3-carboxylic acid. 
Clothing: Wear appropriate protective clothing to prevent skin exposure. 
Respirators:Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

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