2013年12月3日星期二

Possible side effects of Docusate sodium

Docusate sodium is used to make stools softer and easier to pass. It is used in symptomatic treatment of constipation, and in painful anorectal conditions such as hemorrhoids and anal fissures for people avoiding straining during bowel movements.

Docusate sodium(CAS NO:577-11-7)may be used in people who are undergoing opioid pain therapy, are opioid dependent, or on opioid replacement therapy, though prolonged use may cause irritation of the gastrointestinal tract. Data supporting its efficacy in treating chronic constipation is lacking.

Patients taking Docusate sodium(CAS NO:577-11-7)should drink plenty of water to irrigate the bowel, thereby increasing motility. Given orally, the effects are usually seen 1 to 3 days after the first dose. Given rectally, as an enema or suppository, a bowel movement usually occurs within 5 to 20 minutes.

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects of Docusate sodium have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.

Stomach pain, diarrhea, or cramping may occur. Irritated throat (with liquid or syrup forms) may also occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

If your doctor has directed you to use Docusate sodium, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor immediately if this unlikely but serious side effect occurs: rectal bleeding.

A very serious allergic reaction to Docusate sodium is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US-Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. In Canada- Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

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