2013年12月10日星期二

Take care of 2-Bromo-3-hydroxypyridine in 4 aspects

2-Bromo-3-hydroxypyridine, its systematic name is 2-bromopyridin-3-ol. It should be sealed and stored in a cool and dry place. Moreover, it should be protected from light. It is used in organic synthesis.It can be used to produce 2-bromo-3-isopropoxypyridine at the temperature of 80 C. It will need reagent K2CO3 and solvent dimethylformamide with the reaction time of 2 hours.

1.Summary of the Hazards 

When you are using 2-Bromo-3-hydroxypyridine(CAS NO:6602-32-0), please be cautious about it as the following: 2-Bromo-3-hydroxypyridine is harmful by inhalation, in contact with skin and if swallowed. It is irritating to eyes, respiratory system and skin; in case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice, when using it, you need wear suitable protective clothing and must avoid contact with eyes.

2.First Aid Measures

Eyes:
Check for and remove any contact lenses. IMMEDIATELY flush eyes with runing water for at least 15 minutes; Keeping eyelids open. COLD water may be used; DO NOT use an eye oitment. Flush eyes with running water for a minimum of 15 minutes, occasionally lifting the upper eyelids. Seek medical attention. Treat symptomatically and supportively.

Skin:
If 2-Bromo-3-hydroxypyridine(CAS NO:6602-32-0) contact with skin, wash immediately with plenty of water. Gently and thorough wash the contaminated skin with running water and non-abrasive soap; Be particularly careful to clean folds, crevices, creases and groin; COLD water may be used; Cover the irritated skin with an emollient. Seek medical attention. Treat symptomatically and supportively. Wash any contaminated clothing before reusing.

Inhalation:
If the victim is not breathing, perform artificial respiration. Loosen tight clothing such as a collar, tie, belt or waistband. If breathing is difficult, oxygen can be administered; Seek medical attention. Treat symptomatically and supportively.

Ingestion:
INDUCE VOMITING by sticking finger in throat. Lower the head so that the vomit will not reenter the mouth and throat; Loosen tight clothing such as a collar, tie, belt, or waistband. If the victim is not breathing, administer artificial respiration. Examine the lips and mouth to ascertain whether the tissues are damaged, a possible indication that the toxic material was ingested; the absence of such signs, however, is not conclusive. Seek immediate medical attention and, if possible, show the chemical label. Treat symptomatically and supportively.

3.Accidental Release Measures

In case of a spill or a leak, always shut off any sources of ignition, ventilate the area, and exercise caution. Use a shovel to put the material into a convenient waste disposal container; Finish cleaning the spill by rinsing anycontaminated surfaces with copious amounts of water; Consult federal, state, and/or local authorities for assistance on disposal.

4.Handling and Storage

Keep 2-Bromo-3-hydroxypyridine away from heat and sources of ignition. Mechanical exhaust required; When 2-Bromo-3-hydroxypyridine is not in use, tightly seal the container and store in a dry, cool place. Avoid excessive heat and light. Do not breathe 2-Bromo-3-hydroxypyridine dust; Always store 2-Bromo-3-hydroxypyridine away from incompatible compounds such as oxidizing agents.

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