Details about Trimethyl orthoformate

Chemical characters:

English name: Trimethyl orthoformate
English Synonyms: Methyl orthoformate; Orthoformic acid trimethyl ester; Thrimethyl orthoformate; Trimethoxymethane.
Molecular Formula: C4H10O3
Molecular Weight: 106.12
EINECS: 205-745-7
CAS NO.: 149-73-5

Physical characters:

Density: 0.97
Melting point: -53 º C
Boiling Point: 101-102 º C
Refractive index: 1.378-1.38
Flash point: 13 º C
Water solubility: 10 G / L (hydrolysis)

Trimethyl orthoformate is a colorless liquid that can dissolve in alcohol, ether, benzene, it will decompose when combined with water.

Mainly Usage:

Trimethyl orthoformate is the important intermediate for the production of vitamin B1, sulfa drugs, antibiotics and other drugs, it is also used as additive for spices, pesticide materials and polyurethane coating.

Safety Statements：

The Hazard Signs of Trimethyl orthoformate are “F” and “Xi”, Trimethyl orthoformate is a kind of Flammable and Irritant chemicals. It is so Highly flammable and Irritating to eyes, we should be careful for it. Here are the Safety Phrases: 
Keep Trimethyl orthoformate away from sources of ignition.
In case of the drug contact with eyes, rinse immediately with plenty of water and seek medical advice.
Do not empty Trimethyl orthoformate into drains.
Keep container with Trimethyl orthoformate in a well-ventilated place.

Preparation Products And Raw:

Raw materials: Sodium hydroxide -> Na -> Chloroform
Preparation Products: N-methyl-P-anisidine -> N-tert-butoxycarbonyl-5 ,6,7,8 - tetrahydro-3 - methoxy - [1,2,4] triazolo [4, 3-A] pyrazine -> 6 - bromo-4-chloro - quinoline -> 4,7 - dimethoxy-1, 10 - phenanthroline -> 4 - (trifluoromethyl)-N-methyl-aniline -> 3 - methoxy-N-methyl aniline -> 6 - bromo-quinoline -4 (3H) - one -> PPA -> methyl methanesulfonate

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