Synonyms: Glutamine,N-ethyl-, L- (6CI,7CI,8CI); Ng-Ethyl-L-glutamine; Suntheanine; Theanin; Theanine; L-Theanine
Molecular Weight: 174.19766 [g/mol]
Molecular Formula: C7H14N2O3
H-Bond Donor: 3
H-Bond Acceptor: 4
Rotatable Bond Count: 5
Tautomer Count: 2
CAS NO.: 3081-61-6
L-Glutamine,N-ethyl- also gamma-glutamylethylamide or 5-N-ethyl-glutamine, is an amino acid and a glutamic acid analog primarily found in tea , and also in the basidiomycete mushroom Boletus badius and in guayusa. The L-enantiomer is the form which is found in tea and used as a supplement by humans.
L-Glutamine,N-ethyl- was discovered as a constituent of green tea in 1949 and was approved in Japan in 1964 for unlimited use in all foods, including chocolates, soft drinks, and herb teas, except infant foods. It also provides a unique umami (brothy or savory) taste and flavor to green tea infusion.
Arly studies of L-Glutamine,N-ethyl- involved much larger doses than are found in an everyday cup of tea. Researchers wonder whether drinking tea might have the same effects found in those studies. However, one recent study by Unilever found that smaller doses typical of those found in a cup of tea did induce changes in alpha waves as shown by EEG. Alpha waves occur in the brain and are associated with relaxation.
Able to cross the blood-brain barrier, L-Glutamine,N-ethyl- has psychoactive properties.L-Glutamine,N-ethyl- has been studied for its potential ability to reduce mental and physical stress, improve cognition, and boost mood and cognitive performance in a synergistic manner with caffeine.
While structurally related to the excitatory neurotransmitter glutamate, L-Glutamine,N-ethyl- only has weak affinity for the glutamate receptor on postsynaptic cells. Rather, its primary effect seems to increase the overall level of the brain inhibitory transmitter GABA. L-Glutamine,N-ethyl- also increases brain dopamine levels and has a low affinity for AMPA, kainate, and NMDA receptors. Its effect on serotonin is still a matter of debate in the scientific community, with studies showing increases and decreases in brain serotonin levels using similar experimental protocols. It has also been found that injecting spontaneously hypertensive mice with L-Glutamine,N-ethyl- significantly lowered levels of 5-hydroxyindoles in the brain. Researchers also speculate it may inhibit glutamic acid excitotoxicity. L-Glutamine,N-ethyl- also promotes alpha wave production in the brain.
Studies on test rats have shown even repeated, extremely high doses of L-Glutamine,N-ethyl- cause little to no harmful psychological or physical effects. L-Glutamine,N-ethyl- showed neuroprotective effects in one rat study.
A placebo-controlled trial has shown adding L-Glutamine,N-ethyl- to ongoing antipsychotic medication is helpful in reducing some symptoms of schizophrenia.Several beverage manufacturers are selling drinks containing L-Glutamine,N-ethyl- and are marketing them as drinks to help people focus and concentrate, while other manufacturers claim relaxing and tranquillizing properties.
Want to learn more information about L-Glutamine,N-ethyl-, you can access the guidechem.com. Guidechem.com is just a place for you to look for some chemicals. Guidechem provide the most convenient conditions for the international buyers and let these leads benefit all the business people.
没有评论:
发表评论