Before taking Etodolac

Etodolac is a nonsteroidal anti-inflammatory drug. The U.S. Food and Drug Administration approved etodolac in January 1991. It is a kind of crystalline solids with Molecular Formula:C17H21NO3 and Molecular Weight:287.36. It is slightly soluble, stable at normal temperatures and pressures. The CAS Registry Number is 41340-25-4.

Etodolac is a non-steroidal anti-inflammatory drug. Non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2 (COX-2) (IC 50 values are 53 and >100μM for COX-2 and COX-1 respectively). Displays anti-inflammatory effects in both adjuvant arthritic and normal rats.

Etodolac(CAS NO: 41340-25-4) is used for the management of mild to moderate pain, fever, and inflammation. They work by reducing the levels of prostaglandins, which are chemicals that are responsible for pain and the fever and tenderness that occur with inflammation. Etodolac blocks the enzyme that makes prostaglandins, resulting in lower concentrations of prostaglandins. As a consequence, inflammation, pain and fever are reduced.

Post-marketing studies demonstrated that etodolac inhibition of cyclooxygenase is somewhat COX-2 selective similar to celecoxib and other "COX-2 inhibitors." Unlike rofecoxib, both etodolac and celecoxib can fully inhibit COX-1 and are designated as having "preferential selectivity" toward COX-2. The (inactive against COX) r-enantiomer of etodolac inhibits beta-catenin levels in hepatoma cells.

Etodolac is a nonsteroidal anti-inflammatory drug (NSAIDs). It works by reducing hormones that cause inflammation and pain in the body. NSAIDs treat the symptoms of pain and inflammation. They do not treat the disease that causes those symptoms. It is used to treat pain or inflammation caused by arthritis or osteoarthritis. It may also be used for purposes other than those listed in this medication guide.

Take Etodolac by mouth as directed by your doctor, usually 2 or 3 times a day with a full glass of water (8 ounces/240 milliliters). Do not lie down for at least 10 minutes after taking this drug. To prevent stomach upset, take this medication with food, milk, or an antacid.

The dosage is based on your medical condition and response to treatment. To reduce your risk of stomach bleeding and other side effects, take Etodolac at the lowest effective dose for the shortest possible time. Do not increase your dose or take it more often than directed. For ongoing conditions such as arthritis, continue taking Etodolac as directed by your doctor.

If you are taking Etodolac "as needed", remember that pain medications work best if they are used as the first signs of pain occur. If you wait until the pain has worsened, the medication may not work as well.

If you need take Etodolac, you should pay more attention to it. Learning more health information, properties or suppliers about Etodolac, you can access Guidechem.