What is 17-methyltestosterone?

17-methyltestosterone is a white to off-white crystalline powder, it is stable under normal temperatures and pressures, the Density is 112, Boiling Point is 104-116 C, Melting Point is 162-168 C, and Flash Point is 185.3 C. It has the Molecular Formula:C20H30O2, and Molecular Weight:302.451. The CAS Registry Number is 58-18-4.

17-methyltestosterone is a synthetic anabolic steroid used for treating men with testosterone deficiency or similar androgen replacement therapies. Also, has antineoplastic properties and so has been used secondarily in women with advanced breast cancer. In fish culture, used to produce monosex populations of those species which tend to overpopulate

17-methyltestosterone(CAS NO:58-18-4) is a steroid hormone from the androgen group. It is primarily secreted from the testes of males. In females, it is produced in the ovaries, adrenal glands and by conversion of adrostenedione in the periphery. It is the principal male sex hormone and an anabolic steroid.

In both males and females, it plays key roles in health and well-being. Examples include enhanced libido, energy, immune function, and protection against osteoporosis. On average, the adult male body produces about twenty times the amount of testosterone than an adult female's body does.

The effects of 17-methyltestosterone in humans and other vertebrates occur by way of two main mechanisms: by activation of the androgen receptor (directly or as DHT), and by conversion to estradiol and activation of certain estrogen receptors. 

Free 17-methyltestosterone is transported into the cytoplasm of target tissue cells, where it can bind to the androgen receptor, or can be reduced to 5α-dihydrotestosterone (DHT) by the cytoplasmic enzyme 5α-reductase. DHT binds to the same androgen receptor even more strongly than T, so that its androgenic potency is about 2.5 times that of T. 

The T-receptor or DHT-receptor complex undergoes a structural change that allows it to move into the cell nucleus and bind directly to specific nucleotide sequences of the chromosomal DNA. The areas of binding are called hormone response elements (HREs), and influence transcriptional activity of certain genes, producing the androgen effects.

The Side effects of 17-methyltestosterone include amnesia, anxiety, discolored hair, dizziness, dry skin, hirsutism, hostility, impaired urination, paresthesia, penis disorder, peripheral edema, sweating, and vasodilation.

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