Summary the usages of Acetophenone

Acetophenone is the organic compound with the Molecular Formula C8H8O. It is the simplest aromatic ketone. This colourless, viscous liquid is a precursor to useful resins and fragrances. It is stable, incompatible with strong oxidizing agents, strong bases, strong reducing agents and combustible. The Molecular Weight is 120.15, EINECS is 202-708-7 and CAS Registry Number is 98-86-2.

It can be obtained by a variety of methods. In industry, acetophenone is recovered as a by-product of the oxidation of ethylbenzene, which mainly gives ethylbenzene hydroperoxide for use in the production of propylene oxide.

Acetophenone(CAS NO:98-86-2) is a useful and very common synthetic precursor. It’s one of a relatively few chemicals that aren’t used as a solvent that many labs keep around in liter bottles. The main reason I like it, though, is that it smells wonderful.

Summary the usages of Acetophenone: In perfumery to impart an orange-blossom-like odor, catalyst for polymerization of olefins, in organic synthesis, esp as photosensitizer.It is used in perfumery. Like many single chemicals, its smell is puzzlingly hard to pin down smells, such as coffee, where you definitively say that’s it,are very often mixtures. I’d describe it as something like orange blossom with a bit of artificial cherry/almond.

Acetophenone also is of note for its use in Luca Turin’s experiment-a controversial dark-horse theory of olfaction that says vibrational levels of a molecule hold predictive power for odorant character. In one experiment, he found that he could order a perdeuterated acetophenone. Turin and some others insist they smell different, others insist isotope-exchanged compounds are indistinguishable.

When used in pharmaceutical and related areas, it is a raw material for the synthesis of some pharmaceuticals, examples include dextropropoxyphene and phenylpropanolamine. When it used as Niche, is an ingredient in fragrances that resemble almond, cherry, honeysuckle, jasmine, and strawberry. It is used in chewing gum. It is also listed as an approved excipient by the U.S. FDA. In a 1994 report released by five top cigarette companies in the U.S., acetophenone was listed as one of the 599 additives to cigarettes.

In instructional laboratories, acetophenone is converted to styrene in a two step process that illustrates the reduction of carbonyls and the dehydration of alcohols.A similar process is used industrially but the hydrogenation step to 1-phenylethanol is done over a copper catalyst. Being prochiral, acetophenone is also a popular test substrate for asymmetric transfer hydrogenation experiments.

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