2014年1月19日星期日

What is Spironolactone mainly used for ?

Spironolactone is a synthetic, a white powder, commonly referred to simply as "spiro", and marketed primarily under the brand name Aldactone in most countries. The Molecular Formula is C24H32O4S, Molecular Weight is 416.57.

Spironolactone is stable under normal temperatures and pressures. Keep container closed when not in use. Store it in a cool, dry, well-ventilated area away from incompatible substances. Competitive mineralocorticoid (aldosterone) receptor antagonist that exhibits antihypertensive activity in vivo . Also displays antiandrogen activity and inhibits steroid hormone biosynthesis. The CAS Registry Number is 52-01-7.

Spironolactone is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypok.

As an important medicine, Spironolactone(CAS NO: 52-01-7) has been used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It is also used to treat swelling (edema) caused by certain conditions (congestive heart failure) by removing excess fluid and improving symptoms such as breathing problems.

Spironolactone is a potent antagonist of the androgen receptor as well as an inhibitor of androgen production. Due to the antiandrogenic effects that result from these actions, it is frequently used to treat a variety of cosmetic conditions in which androgen hormones such as testosterone and dihydrotestosterone (DHT) play a role, including hirsutism, androgenic alopecia, acne, and seborrhea in females, and male pattern baldness in either low doses or as a topical formulation in males; higher doses are not recommended for males due to the high risk of feminization and other side effects. In addition, it is also commonly used to treat symptoms of hyperandrogenism in polycystic ovary syndrome.

It is also used to treat low potassium levels and conditions in which the body is making too much of a natural chemical (aldosterone). Spironolactone is known as a "water pill" (potassium-sparing diuretic).

Spironolactone is used to diagnose or treat a condition in which you have too much aldosterone in your body. Aldosterone is a hormone produced by your adrenal glands to help regulate the salt and water balance in your body.

Spironolactone also treats fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or a kidney disorder called nephrotic syndrome. It is also used to treat or prevent hypokalemia (low potassium levels in the blood).

If you need take Spironolactone, you should pay more attention to it. Learning more health information, properties or suppliers about Spironolactone, you can access Guidechem. Guidechem chemical B2B network provides information on china and global chemical market quotation and relative chemical Information.

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